Scavenging and antioxidant activities of immunomodulating polysaccharides isolated from Salvia officinalis L.

Capek, Peter; Machová, Eva; Turjan, J.

doi:10.1016/j.ijbiomac.2008.10.007

Cited by 54 publications

(11 citation statements)

References 28 publications

(28 reference statements)

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“…Of the herbal medicines found to have the highest antiadhesive activity in this study, C. officinalis , S. officinalis , T. officinale root and G. glabra root have been shown to contain polysaccharides such as arabinogalactan in the case of sage (Capek et al , ), and polysaccharides enriched with glucuronic acid in the case of G. glabra (Wittschier et al , ). Polysaccharides are probably less likely to be responsible for the activity of calendula and sage in this investigation due to the high ethanol concentration of the extraction solvent used (see Table ).…”

Section: Discussionmentioning

confidence: 81%

Investigations into the Antiadhesive Activity of Herbal Extracts Against Campylobacter jejuni

Bensch

Tiralongo²,

Schmidt

et al. 2011

Phytotherapy Research

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Campylobacter jejuni is one of the most common bacterial causes of diarrhoea in the industrialized world, being associated with the occurrence of Guillain-Barré Syndrome, and inducing diseases partially through intestinal adherence. With increasing reports of C. jejuni drug resistance against standard antibiotics, investigations into antiadhesive agents for the prevention of bacterial infection are highly significant. Given the consumer-driven development towards holistic and integrative healthcare, research into additional anti-Campylobacter effects of herbal medicines that are already used for their beneficial effects on bowel and digestive functions is important. Twenty-one herbal extracts were screened for antiadhesive activity against C. jejuni using modifications of previously published antiadhesion assays. Antiadhesion effects with IC(50) values <3 mg/mL were obtained for seven ethanol plant extracts, with Zingiber officinale (ginger), Capsicum annum (cayenne) and Glycyrrhiza glabra (licorice) displaying the highest antiadhesion activity against C. jejuni (IC(50) : <0.1 mg/mL, 0.29 mg/mL and 0.65 mg/mL, respectively). Differences in antiadhesion activity were found for two different Echinacea species, with E. purpurea displaying significantly higher and dose dependent antiadhesion activity than E. angustifolia. No significant antiadhesion activity (IC(50) values >35 mg/mL) was found for Agrimonia eupatoria (agrimony), Andrographis paniculata (andrographis), Matricaria recutita (chamomile), Foeniculum vulgare (fennel), Filipendula ulmaria (meadowsweet) and Artemisia absinthium (wormwood) extracts. This study provides evidence for additional beneficial effects of marketed herbal medicines in gastrointestinal disorders.

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Section: Discussionmentioning

confidence: 81%

Investigations into the Antiadhesive Activity of Herbal Extracts Against Campylobacter jejuni

Bensch

Tiralongo²,

Schmidt

et al. 2011

Phytotherapy Research

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“…Antioxidant and antimicrobial activities of extracts obtained from herb and SPM of S. glutinosa by ultrasound-assisted extraction (UE) and classical solvent extraction (CE) using methanol and 70% v/v aqueous ethanol as extracting solvents were studied. S. officinalis was included as a reference plant due to its wellknown antioxidant [18,20] and antimicrobial [16,[21][22][23] activities. The main goal was to compare antioxidant and antimicrobial activities of extracts obtained by various extraction techniques.…”

mentioning

confidence: 99%

Comparison of antioxidant and antimicrobial activities of extracts obtained from Salvia glutinosa L. and Salvia officinalis L.

Veličković

Karabegović²,

Stojičević³

et al. 2011

Hem Ind

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Antioxidant and antimicrobial activities as well as total phenols and flavonoids contents of Salvia glutinosa L. (glutinous sage) and Salvia officinalis L. (sage) extracts were studied. Methanol and aqueous ethanol (70% v/v) were used for extraction of bioactive compounds, both in the presence and the absence of ultrasound, from herb and the spent plant material remaining after the essential oil hydrodistillation. The ratio of plant material to extracting solvent was 1:10 g/ml. Antioxidant and antimicrobial activities of the extracts were found to depend on the type of plant material and the extraction conditions. The plant materials from which essential oil had been recovered were proven to be valuable raw materials for making various herbal preparations

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“…According to previous studies, a low molecular weight and a relatively high protein content appeared to increase the antioxidant activity (Chen and others 2008b; Song and others 2010), perhaps TFP‐2 with low molecular weight and relatively high protein contents might bind radicals more easily. Moreover, some polysaccharides contain uronic acids were shown to exhibit high biological effects because uronic acid residues could alter polysaccharides’ properties and modify the solubility, the carboxyl groups of the uronic acid also might play the role of hydrogen‐donating and electron‐transfer agent, suggesting that varieties or contents of monosaccharides possibly contribute to the biological effects (Chen and others 2004; Capek and others 2009). Previous literature also reported the electron‐withdrawing groups (acetyl), which were detected in 1 H NMR spectra, appear to function as good hydrogen atom donors and therefore should be able to terminate radical chain reactions by converting free radicals to more stale products (Yanagimoto and others 2002).…”

Section: Discussionmentioning

confidence: 99%

Structural Characterization and Antioxidant Activities of 2 Water‐Soluble Polysaccharide Fractions Purified from Tea (Camellia sinensis) Flower

Han

Shi

et al. 2011

Journal of Food Science

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At present, commonly low-grade tea is preferred to extract the tea polysaccharide, to take full advantage of tea flower resource to extract polysaccharides can greatly reduce the cost of tea products. Thus, the search for plant-derived biomaterials from this study could generate natural value-added products from underutilized tea plant waste and used as a medicinal agent against chronic health problems, such as cancers, aging, and atherosclerosis caused by reactive free radicals that produced from oxidation.

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Scavenging and antioxidant activities of immunomodulating polysaccharides isolated from Salvia officinalis L.

Cited by 54 publications

References 28 publications

Investigations into the Antiadhesive Activity of Herbal Extracts Against Campylobacter jejuni

Investigations into the Antiadhesive Activity of Herbal Extracts Against Campylobacter jejuni

Comparison of antioxidant and antimicrobial activities of extracts obtained from Salvia glutinosa L. and Salvia officinalis L.

Structural Characterization and Antioxidant Activities of 2 Water‐Soluble Polysaccharide Fractions Purified from Tea (Camellia sinensis) Flower

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