Abstract:BackgroundTNFα is one of the most important cytokine in the pathogeneses of poly-JIA. There are several TNF inhibitors for the treatment poly-JIA. Switching TNF-blockers is often strategy in the treatment of poly-JIA.MethodsAn open observational study in patients with poly-JIA taking the second TNFinhibitor. A total of 119 patients (46 boys and 73 girls) were included in this study. The mean age was 11 (7;14), disease duration was 5 (3;8) years. By the switching time 54/119 had active polyarthritis, 58/119 – o… Show more
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