Sasang constitutional types can act as a risk factor for insulin resistance

Choi, K. M.; Lee, Jiwon; Yoo, Jung-Hee; Lee, Euiju; Koh, Byung-Hee; Lee, Junhee

doi:10.1016/j.diabres.2010.11.017

Cited by 52 publications

(53 citation statements)

References 14 publications

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“…In East Asian Medicine, it is thought that the process by which an individual can display his/her vitality can vary. Starting from a simple difference of degree such as strength and weakness, the variation can reach constitutional differences as mentioned by the 19th century Korean medical scholar, Lee Jema (Cha et al, 2007;Choi et al, 2011;Park et al, 2011). East Asian medical scholars were curious about different responses displayed in the same environment, and made efforts to explain such differences.…”

Section: Discussionmentioning

confidence: 99%

Therapeutic effects of traditional Korean medicine, Jeechool-Whan in allergic rhinitis model

Oh¹,

Ryu²,

Cha³

et al. 2012

TANG [HUMANITAS MEDICINE]

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Jeechool-Whan (JW) is a prescription of Ponciri Fructus Immaturus and Atractylodis Rhizoma Alba and improves the functions of the stomach and the spleen. Although it is said in Korean Medicine that the spleen and the stomach are the roots of the body's resistance, the meaning of 'improving the spleen and the stomach' is very comprehensive. Moreover, there are lots of drugs that are said to improve the spleen and the stomach, and the number of prescriptions using these drugs is huge. In this study, we focused on the new effect and mechanism of the JW on the ovalbumin (OVA)-induced allergic rhinitis (AR) model. The increased number of rubs and the increased levels of IgE and histamine in the OVA-sensitized mice were inhibited by JW administration. The balance of Th1/Th2 cytokine level was regulated by JW administration. The levels inflammatory proteins were decreased by JW administration in the nasal mucosa of the OVA-sensitized mice. Eosinophils and mast cells infiltration increased by OVAsensitization was also decreased in the JW-administered mice. In addition, JW inhibited caspase-1 activity in the same nasal mucosa tissue. In activated human mast cells, JW inhibited the receptor interacting protein-2, IκB kinase-β, nuclear factor-κB/Rel A, and caspase-1 activation. In conclusion, this study will be support the clear understanding of the concept of the spleen and the stomach in traditional Korean medicine as well as for a possibility of finding a cure for this AR in traditional medical treatments.

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Section: Discussionmentioning

confidence: 99%

Therapeutic effects of traditional Korean medicine, Jeechool-Whan in allergic rhinitis model

Oh¹,

Ryu²,

Cha³

et al. 2012

TANG [HUMANITAS MEDICINE]

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“…Several clinical studies have also suggested that the TE type is associated with overweight or obesity by merely describing different BMI in the general characteristics according to SC [16–19, 23], which indicates that weight characterizes specific SC. However, these studies did not report the prevalence of obesity as indicated by BMI, WC and WHR according to SC or how much specific SC (e.g., the TE type) is associated with higher risk compared to a reference SC (e.g., the SE type).…”

Section: Introductionmentioning

confidence: 99%

The prevalence of general and abdominal obesity according to sasang constitution in Korea

Baek

Park

Lee

et al. 2014

BMC Complement Altern Med

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BackgroundObesity is an important risk factor for cardiovascular and metabolic diseases and could affect mortality rates. Body mass index (BMI) and waist circumference (WC) have been used to classify obesity, and waist-to-hip ratio (WHR) has recently emerged as a discriminator of cardiovascular disease. Sasang constitution (SC) is a kind of well-known traditional Korean medicine: Tae-eumin (TE), Soeumin (SE), Taeyangin (TY) and Soyangin (SY) carrying a different level of susceptibility to chronic diseases. We aimed to examine the prevalence in general and abdominal obesity (AO) using BMI, WC and WHR according to SC in the Korean population.MethodsA total of 3,348 subjects were recruited from 24 Korean medicine clinics. Obesity was divided into three categories: general obesity by BMI, abdominal obesity by waist circumference (WC AO) and abdominal obesity by waist-to-hip ratio (WHR AO). A Chi-square test was performed to compare prevalence, and logistic regression was conducted to generate odds ratios (ORs) according to SC (p < .05).ResultsThe prevalence of general obesity was significantly higher in males than in females. The highest prevalence of general obesity, WC AO and WHR AO were all observed in the TE type, and the SY and SE types were followed in order, for both males and females respectively.The TE type was highly associated with increased risk of general obesity (OR = 20.2, 95% CI: 12.4-32.9 in males and OR = 14.3, 95% CI: 10.1-20.2 in females), of WC AO (OR = 10.7, 95% CI: 7.2-15.9 in males and OR = 7.5, 95% CI: 5.8-9.6 in females), and of WHR AO (OR = 4.6, 95% CI: 3.3-6.4 in males and OR = 3.8, 95% CI: 2.9-4.9 in females) compared with the SE type. In addition, after controlling for age, social status and eating habits, the ORs were similar to the crude model according to gender and SC.ConclusionsThis study shows that the prevalence of obesity varies according to SC in the Korean population. In particular, the TE type was highly associated with increased ORs for general obesity, WC AO and WHR AO in both genders.

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“…More remarkably, the BMI distribution profiles are also established, with many studies reporting obesity-prone characteristics in the TE type 20,21) . The prevalence and risk rates for other chronic diseases are also known to vary among the Sasang Jiwon Lee, et al: Sasang Constitutional Type as a Risk factor for Dyslipidemia constitution types, such as for hypertension 16) , type 2 diabetes mellitus 15) , insulin resistance 14) , and ischemic cerebrovascular diseases 22) . Similarly, the results of this study indicate constitutional type-specific lipid profiles and dyslipidemic risk, specifically that the TE constitution-type trait can act as an independent risk factor for dyslipidemia.…”

Section: Comparison Of Lipid Profiles Across the Different Constitutimentioning

confidence: 99%

“…[11][12][13] . Also, recent evidence suggests that the Sasang constitution types can be a predictor of the risk for several conditions including insulin resistance, type 2 diabetes mellitus and hypertension [14][15][16] .…”

Section: Introductionmentioning

confidence: 99%

Can the Sasang Constitutional Type Trait Act as an Independent Risk Factor for Dyslipidemia?

이지원¹,

장현수²,

박병주³

et al. 2014

JKOMOR

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Sasang constitutional types can act as a risk factor for insulin resistance

Cited by 52 publications

References 14 publications

Therapeutic effects of traditional Korean medicine, Jeechool-Whan in allergic rhinitis model

Therapeutic effects of traditional Korean medicine, Jeechool-Whan in allergic rhinitis model

The prevalence of general and abdominal obesity according to sasang constitution in Korea

Can the Sasang Constitutional Type Trait Act as an Independent Risk Factor for Dyslipidemia?

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