Sarcoma de Kaposi y angiosarcoma cutáneo: directrices para el diagnóstico y tratamiento

Cutaneous Angiosarcoma in an Unusual Location and Without Predisposing Factors

“…An adequate histological assessment is necessary and it is usually supported by immunohistochemistry features to establish the diagnosis [2] . Our case showed characteristic histopathological features, namely atypical endothelial proliferation of epithelioid and spindle cells, with frequent mitotic figures and necrosis [3] . Immunochemistry was the key to the diagnosis by identifying expression of CD31, CD34, and factor VIII antigen.…”

“…Soft tissue sarcomas are a heterogeneous group that represents 1% of solid malignant tumours [1] . Angiosarcomas represent 1-2% of all sarcomas [2,3] and can affect the skin, soft tissue, breasts or liver. The most common angiosarcoma site is the skin [2,3] .…”

“…Angiosarcomas represent 1-2% of all sarcomas [2,3] and can affect the skin, soft tissue, breasts or liver. The most common angiosarcoma site is the skin [2,3] . Cutaneous angiosarcomas are extremely rare soft tissue tumours, of capillary and lymphatic endothelial cell origin.…”

“…Cutaneous angiosarcomas are extremely rare soft tissue tumours, of capillary and lymphatic endothelial cell origin. It presents more commonly in men with a median age of 73 years, mostly in the head and neck [3] . 3 4] .…”

“…Our case is one of the few reported cutaneous angiosarcomas arising on the lower extremities in the absence of predisposing factors such as chronic lymphoedema or prior radiation therapy. Clinically, cutaneous angiosarcoma usually resembles a bruise, blue to red colour, with a multifocal nodular component that develops as the tumour progresses [2,3] . Also, with increasing size, tissue infiltration, oedema, ulceration and bleeding can occur, as in our patient.…”