Sarcoidosis and the Acoustic Nerve

Audiovestibular Manifestations of Sarcoidosis: A Review of the Literature

“…Thirty‐three references providing 48 suitable case reports were identified for the case report summary 3–35 . Inclusion of the two patients from the clinics resulted in a total of 50 cases.…”

Neuro‐otologic manifestations of sarcoidosis

“…Through 1958 there were only 10 case reports of spinal cord involvement.7 Pathologically three basic pictures are seen: diffuse microgranulomas in brain substance, large confluent granulomas seen only in the brain and myocardium or meningeal granulomatosis. 8 Of these, infiltration of the basal meninges may be the most common pathologic process. 2 ,4 Clinically there are two general classifications for neurologic lesions (Table II): neuropathies, involving either cranial or peripheral nerves, and central nervous system involvement.…”

“…The similarities to Cogan's syndrome and Vost-Koyanagi-Harada's disease suggest that an altered immunologic response, i.e., a vasculitis, is responsible for the otologic symptoms. 8 It is possible to deduce also that the more central the lesion, the poorer the prognosis. Up to 1969, only 19 cases of cochlear or vestibular symptoms had been recorded in the literature.…”

“…Up to 1969, only 19 cases of cochlear or vestibular symptoms had been recorded in the literature. 8 Certain associations with involvement of the vestibular or acoustic system exist. In one series of 12 cases of neurosensory hearing loss secondary to sarcoidosis, eight patients had a vestibular disturbance and an equal number had a facial paralysis.…”

An unusual presentation of neurosarcoidosis with progressive hearing loss

“…When it presents as the initial symptom of NS, whether unilateral or bilateral, it has a sudden or rapidly progressive onset 90% of the time [ 5 ]. There have been few reports describing it as one of the initial presenting symptoms of sarcoidosis in otherwise undiagnosed patients, however these were also associated with other neurological or ENT disturbances [ 6 , 7 ]. The diagnosis of neurosarcoidosis is based on clinical and radiological correlation in combination with a tissue biopsy [ 8 , 9 ].…”