Sarcoid Associated With Tuberculosis of the Larynx

Sarcoidosis of the upper respiratory tract and its association with lupus pernio.

“…SURT may be complicated by nasal septal or palatal perforations so submucous resection is not recommended if the original biopsy reveals sarcoid tissue. We confirm septal or palatal perforation noted in three earlier reports (Allison and Mikell, 1932;Barmwater, 1936;Lindsay and Perlman, 1951). In two of these three patients, submucous resection was also an aetiological factor.…”

Sarcoidosis

“…We have reviewed 116 recorded cases of generalized sarcoidosis in which granulomas were found clinically in the nasal cavities and histologically confirmed (Ulrich, 1918 ;Allison and Mikell, 1932;Novy, 1936;Kistner and Robertson, 1938;Seifert, 1939;Poe, 1940 a andb, 1942, the same case being reported later by Poe and Seager, 1950;Bordley and Proctor, 1942;Wille, 1946;Rubin and Kling, 1948 ;Robinson and Pound, 1950, Case 13;Larsson, 1951, Cases 7, 8, 9 and 10;Lindsay and Perlman, 1951 , nine cases;Livingstone, 1956;Ferguson and Paris, 1958, Case 5;Weiss, 1960, three cases;Creston and Dibble, 1961 ;Arova, 1963 ;Siltzbach and Blaugrund, 1963, six cases;Kämpfer, 1964, ten cases;Dowie, 1964, three cases; 292 Sarcoidosis Black, 1966 ;Scadding, 1967, three cases;Mckelvie et al, 1968, 11 cases;Page and Seth, 1969;Di Benedetto and Lefrak, 1970;Carosso, 1974;Wright et al, 1974, two cases;Gordon et al, 1976, three cases;Kirschner et al, 1976;Neville et al, 1976, 17 cases ;Delaney, 1977, Case 1;Selroos and Niemistö, 1977, 11 cases;Maillard and Goepfert, 1978;Allen, 1979;Som and Krespi, 1979;Coup and Hopper, 1980;Hammond and Kataria, 1980). Of the cases in which the sex of the patient was mentioned, 73 were in women and 25 in men; ...…”

“…Perforation of the septum may occur. In several cases, it has been reported after surgical procedures, notably submucous resection of the The Upper Respiratory Tract 293 septum (Allison and Mikell, 1932;Neville et al 1976, two cases;Harnmond and Kataria, 1980). In a few cases, surgical procedures on the septum, with or without inferior turbinectomy, have been undertaken for relief of obstruction without this complication (Wright et al, 1974;Maillard and Goepfert, 1978); and perforation may occur in patients treated conservatively (Barmwater, 1936;Neville et al, 1976, one case).…”

“…Sparing of the cords in the presence of extensive changes elsewhere was noted by Carasso (1974 ), in whose patient the true cords appeared normal although the epiglottis, the ary-epiglottic folds and the false cords were extensively involved causing stridor, and by Kirschner and Holinger (1976) in a 14 year old black male with very extensive sarcoidosis involving epiglottis, arytenoids and aryepiglottic folds, both false vocal cords and the sub-glottic region, but whose true cords showed erythema only. The epiglottis is very frequently affected, either as the only evidently involved part (Barrnwater, 1936, two cases;Seifert, 1939, Lindsay andPerlman, 1951, four cases;Weiss, 1960, Cases 1 and 6;Weisman et al, 1980, Case 1), or with the arytenoids or aryepiglottic folds (Allison and Mikell, 1932;Kämpfer, 1964, Case 5;Devine, 1965;Di Benedetto and Lefrak, 1970;Firooznia et al, 1970, Case 2;Som and Krespi, 1979). Airflow may be obstructed by general thickening of mucosa by widespread granulomatous infiltration or by local polypoid masses; in active stages, the appearances may suggest some oedema, and in the later stages, fibrosis may narrow and distort the laryngeal airway.…”

Upper respiratory tract involvement in sarcoidosis and its management

“…Three out of six patients in our group who had had surgery, but only one out of2l who had not, developed septal perforation. Nasal septal perforation has been reported, both after surgical procedures, notably submucous resection of the septum [2,6,10,11], and after medical treatment alone [2,6,12]. Submucous resection should be avoided in sarcoidosis with nasal involvement.…”