Saprophytic molds as agents of cutaneous and subcutaneous infection in the immunocompromised host

Weitzman, I.

doi:10.1001/archderm.122.10.1161

Cited by 21 publications

(12 citation statements)

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“…Growth of a zygomycete in culture may therefore not represent clinically significant invasive disease. Demonstration of invasive disease by these organisms generally requires the identification of fungal elements directly in the clinical specimen or organism growth from more than one specimen obtained from a normally sterile site (497). When isolates are obtained from nonsterile sites such as sputa, culturing the same organism from multiple specimens or culturing large numbers of colonies from these specimens might suggest the diagnosis; however, these results might also reflect superficial transient colonization.…”

Section: Relationship Of the Zygomycetes To Other Fungi Causing Diseasementioning

confidence: 99%

“…When isolates are obtained from nonsterile sites such as sputa, culturing the same organism from multiple specimens or culturing large numbers of colonies from these specimens might suggest the diagnosis; however, these results might also reflect superficial transient colonization. A positive culture linked to a hyphal identification in cytologic specimens or tissue sections, however, is considered diagnostic (497).…”

Section: Relationship Of the Zygomycetes To Other Fungi Causing Diseasementioning

confidence: 99%

See 1 more Smart Citation

Zygomycetes in Human Disease

Ribes¹,

Vanover-Sams²,

Baker³

2000

Clinical Microbiology Reviews

1,090

1,053

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Section: Relationship Of the Zygomycetes To Other Fungi Causing Diseasementioning

confidence: 99%

Section: Relationship Of the Zygomycetes To Other Fungi Causing Diseasementioning

confidence: 99%

Zygomycetes in Human Disease

Ribes¹,

Vanover-Sams²,

Baker³

2000

Clinical Microbiology Reviews

1,090

1,053

View full text Add to dashboard Cite

“…The term "hyalohyphomycosis" has been used for opportunistic mycotic infection caused by nondematiaceous molds whose basic tissue forms usually consists of septate, branched, or unbranched hyphae forms (1,2). Fusarium is a fungal group that includes approximately 200 species that are rapid growers in Sabouraud's agar or on fungal media without cyclohexamide (3,4).…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Fusarium Infection in an Adolescent with Acute Leukemia

Alvarez-Franco

Reyes‐Múgica

Paller

1992

Pediatric Dermatology

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Disseminated fusariosis occurred in a pediatric patient with acute lymphocytic leukemia in relapse. The patient had fever and neutropenia, and scattered violaceous papules and vesicles with central erosions that rapidly progressed to generalized, painful, violaceous, papulovesicular lesions with central necrosis. Severe myalgias were associated. The diagnosis was suspected by noting hyphae on a smear of vesicular contents, and confirmed by culture. The clinical course was rapidly fatal despite early institution of amphotericin B therapy. Disseminated Fusarium infection should be suspected in immunocompromised patients with fever and neutropenia who have generalized, eroded, violaceous papules, vesicles, and pustules, particularly with associated myalgias.

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“…and Mucor spp. 35,[39][40][41][42] The Rhizopus spp., particularly Rhizopusoryzae , are frequent agents of mucormycosis. Disseminated mucormycosis accounts for about 5% of opportunistic fungal infections in patients with acute leukaemia or lymphoma whose treatment is complicated by leukopenia and broadspectrum antibiotic therapy for concurrent infection.…”

Section: Non-dermatophyte Mold Infectionsmentioning

confidence: 99%

Clinicopathologic presentations of dermatomycoses in cancer patients

Quatresooz¹,

Piérard-Franchimont

Arrese

et al. 2008

Acad Dermatol Venereol

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Many of the skin fungal infections in cancer patients may look similar to those infections in non-cancer patients. However, in some cases, they become more extensive and even life threatening. Prolonged and severe neutropenia is the main risk factor for the dramatic issue of fungal infections. The dermatomycoses in cancer patients can be classified in four broad groups: primary superficial dermatophytoses, primary superficial yeast infections, opportunistic mold infections with distinct potential for dissemination and secondary cutaneous manifestations of fungaemia. Occasionally, more than one fungus are found inside a given skin lesion. A special condition is represented by the mycotic colonization of mucosal squamous cell carcinomas. Angio-invasion by fungi accounts for the frequency of disseminated infections prevailing in immunocompromised cancer patients. In case of skin involvement, the dermatologist may assist by recognizing subtle semiological signs and performing biopsies for swift histological examination, molecular biology and/or culture.

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Saprophytic molds as agents of cutaneous and subcutaneous infection in the immunocompromised host

Cited by 21 publications

References 0 publications

Zygomycetes in Human Disease

Zygomycetes in Human Disease

Cutaneous Fusarium Infection in an Adolescent with Acute Leukemia

Clinicopathologic presentations of dermatomycoses in cancer patients

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