Sample Preparation Strategies for Mass Spectrometry Imaging of 3D Cell Culture Models

Wheatcraft, Dorothy R. Ahlf; Xin, Liu; Hummon, Amanda B.

doi:10.3791/52313-v

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Ma Al Ld DI I--m Ms Si I1

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“…It has been widely used as a technique for the detection of (bio) molecules such as lipids, metabolites, proteins, and peptides, as well as a variety in drugs 101 and polymers 102 in a wide variety of applications 103 along with compound or drug detection, (clinical) diagnostics, biomarker discovery, and identification of potential targets for treatment. Its application involves single cells 104,105 and cell cultures 106,107 , organoids 108,109 , animal-and human organs [110][111][112] , as well as plants and food [113][114][115] , among other.…”

Section: Ma Al Ld DI I--m Ms Si Imentioning

confidence: 99%