Salivary flow rate, buffer capacity, and urea concentration in adolescents with type 1 diabetes mellitus

Busato, Ivana Maria Saes; Antoni, Carlos Cesar De; Calcagnotto, Thiago; Ignácio, Sérgio Aparecido; Azevedo‐Alanis, Luciana Reis

doi:10.1515/jpem-2015-0356

Cited by 15 publications

(16 citation statements)

References 17 publications

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“…Eleven studies reported a DMFT/DMFS index significantly higher among type 1 diabetics, four found a significantly lower index and 20 did not find statistically significant differences between groups.…”

Section: Resultsmentioning

confidence: 87%

“…Forty‐five articles regarding caries experience among type 1 diabetics were analyzed (Table ). Regarding type 2 diabetes 17 studies were included (Table ).…”

Section: Resultsmentioning

confidence: 99%

“…Twelve of the studies were conducted in India, eight in the United States, six in Brazil, five in Finland, four each in Portugal, Sweden, and Turkey, two in Lithuania, one each in Belgium, Bosnia and Herzegovina, China, Egypt, Germany, Hungary, Iraq, Jordan, Republic of Kosovo, Kuwait, Libya, Malaysia, Mexico, Spain, Sudan, Thailand, and Uruguay…”

Section: Resultsmentioning

confidence: 99%

“…The majority of the studies regarding type 1 diabetes only included children . In most studies, the control group was recruited from schools or dental clinics.…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Dental caries,diabetes mellitus, metabolic control and diabetes duration: A systematic review and meta‐analysis

Coelho

Amaro

Caramelo

et al. 2020

J Esthet Restor Dent

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Objective: To analyze articles aimed at evaluating the association between diabetes, metabolic control, diabetes duration, and dental caries.Overview: A systematic search in PubMed, Cochrane Library, Embase, and Web of Science was conducted to retrieve papers in English, Portuguese, and Spanish, up to April 2019. The research strategy was constructed considering the "PECO" strategy.Only quantitative observational studies were analyzed. The risk of bias was assessed using the Newcastle-Ottawa Quality Assessment Scale. The meta-analyses were performed based on random-effects models using the statistical platform R. A total of 69 articles was included in the systematic review and 40 in the meta-analysis. Type

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Section: Resultsmentioning

confidence: 87%

“…Forty‐five articles regarding caries experience among type 1 diabetics were analyzed (Table ). Regarding type 2 diabetes 17 studies were included (Table ).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…The majority of the studies regarding type 1 diabetes only included children . In most studies, the control group was recruited from schools or dental clinics.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Dental caries,diabetes mellitus, metabolic control and diabetes duration: A systematic review and meta‐analysis

Coelho

Amaro

Caramelo

et al. 2020

J Esthet Restor Dent

View full text Add to dashboard Cite

show abstract

“…The stimulated saliva flow rate (SSFR) was evaluated by using a gravimetric method and expressed in mL/minute. SSFR values >0.7 mL/minute were considered to be a normal saliva flow, whereas SSFR values ≤0.7 mL/minute indicated hyposalivation . Xerostomia was assessed from a patient‐centered perspective.…”

Section: Methodsmentioning

confidence: 99%

Salivary shedding of herpesviruses in renal transplant recipients

Sarmento

Caliento

Souza

et al. 2018

J of Invest & Clin Dent

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Caries‐related salivary parameters and oral microbial flora in patients with type 1 diabetes: A meta‐analysis

Ömer

Soğukpınar

Pertek

et al. 2022

Diabetes Metabolism Res

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Objectives: This study aimed to conduct a meta-analysis by synthesising the outcomes of studies that investigated the relationship between type 1 diabetes (T1D) and salivary flow rate (SFR), salivary pH (SpH), salivary buffer capacity (SBC), streptococcus Mutans (SM), and lactobacillus (LB) counts. Material and Methods:The PRISMA statement guide was followed for the metaanalysis. Electronic databases were searched, and study selection and data collection processes were performed. The risks of bias in individual studies and across studies were assessed. Mean differences (MD) and Odds Ratio (OR) were used to measure the effect estimates in the comparisons.Results: 29 studies were included in the qualitative and quantitative syntheses. Significantly higher SFR (MD = −0.22, CI: −0.26, −0.18; p < 0.001) and SpH (MD = −0.59, CI: −0.81, −0.36; p < 0.001) were observed in the healthy individuals than T1D individuals. No significant difference was observed among groups in terms of SBC (MD = 0.10, CI: −0.46,0.66; p = 0.73). An increased odds ratio of SM counts were observed regarding the T1D (OR = 3.09, 95% CI: 1.16, 8.20; p = 0.02). No association was found between LB counts and T1D (OR = 2.15, 95% CI: 0.38, 11.98; p = 0.38).Conclusions: Subjects with T1D have a significantly lesser SFR and SpH than healthy individuals. But no significant difference is available in terms of SBC. Lower SM counts were observed in individuals with T1D, while no association was observed regarding LB counts. The tendency to dental caries is more likely in subjects with T1D due to lower SFR, SpH, and higher SM.

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Salivary flow rate, buffer capacity, and urea concentration in adolescents with type 1 diabetes mellitus

Abstract: In adolescents with type 1 DM, hyposalivation at T0 was associated with an increase in urea salivary concentration. At T1, hyposalivation was associated with a reduction in BC, and an increase in salivary urea.

Cited by 15 publications

References 17 publications

Dental caries,diabetes mellitus, metabolic control and diabetes duration: A systematic review and meta‐analysis

Dental caries,diabetes mellitus, metabolic control and diabetes duration: A systematic review and meta‐analysis

Salivary shedding of herpesviruses in renal transplant recipients

Caries‐related salivary parameters and oral microbial flora in patients with type 1 diabetes: A meta‐analysis

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