Safety and Efficacy of Transcatheter Arterial Embolization for Lower Gastrointestinal Bleeding: A Single-center Experience with 112 Patients

Clinical Outcome of Transcatheter Arterial Embolization With N-Butyl-2-Cyanoacrylate for Control of Acute Gastrointestinal Tract Bleeding

“…In previous case studies that analyzed from 9 to 84 patients, the clinical success rates of TAE with NBCA for gastrointestinal tract bleeding ranged from 82% to 96.4% [11,14,16,23]. Our current study, which included a larger patient sample size, had a success rate of 76.5% (78/102), which is relatively lower than those in previous reports.…”

“…Other potential advantages of NBCA described by previous reports include the capacity of obliteration of the distal small vessel that can be reached by a microcatheter, effective occlusion of bleeding sites with complex anatomy (e.g., tortuous, narrowed, or multiple in-or outflow vessels), and polymerization of NBCA that is not directly affected by coagulopathy [32,33]. However, bowel ischemia after TAE may be significant [11,33,34], and a learning curve for NBCA embolization should be considered [32]. Caution is necessary to avoid inadvertent embolization of nontarget vessels, which may occur because of careless handling of the liquid material or occlusion occurring more rapidly than anticipated.…”

“…NBCA is highly penetrable because of its liquid nature and is less affected by coagulopathies; thus, it may be used as an adjunct to other embolic materials to ensure the embolic effect [9,10]. However, NBCA is difficult to handle effectively and safely and is inherently more prone to cause ischemic necrosis.Although there have been several reports on the use of TAE with NBCA for acute gastrointestinal tract bleeding, 9-84 patients were included in those studies, and neither long-term clinical data nor analyses evaluating clinical factors affecting the clinical success of NBCA were presented [11][12][13][14][15][16]. Therefore, studies in larger patient populations are warranted to determine the clinical effectiveness of NBCA in the setting of acute gastrointestinal tract bleeding, with or AJR 2015; 204:662-668 0361-803X/15/2043-662 © American Roentgen Ray Society E ndoscopy is a rapid diagnostic and therapeutic modality that is widely accepted as the preferred method for identifying and providing hemostasis at sites of gastrointestinal tract bleeding.…”

Superselective Transarterial Embolization for Lower Gastrointestinal Bleeding: An Analysis of its Effectiveness and Safety

“…This result was also comparable to the clinical success rates in other studies, ranging from approximately 63 to 92% (2,(16)(17)(18)(19)(20)(21)(22). In the nine patients classified as clinical failures, the time interval between TAE and early rebleeding was usually short, and the average was approximately three days.…”

“…Also, supplemental particle embolization after microcoil deployment may be helpful in controlling LGI bleeding. A recent study by Hur et al shows the safety and effectiveness of glue as a primary embolic agent for LGI bleeding (22). Although glue embolization is useful for patients with coagulopathy, it requires the operator to have a high level of skill and experience and sufficient training to avoid complications.…”