Safety and efficacy of delivering high-power short-duration radiofrequency ablation lesions utilizing a novel temperature sensing technology

Abstract

Delivery of high-power short-duration RF energy applications, facilitated by a novel ablation catheter system equipped with advanced TC technology, is feasible, safe, and results in the formation of effective ablation lesions.

High-power, Short-duration Radiofrequency Ablation for the Treatment of AF

“…For this reason, all studies advocating HPSD ablation strongly recommend the use of an automatic temperature cutoff. The exact cutoff varies between studies between 50°C and 80°C 8,14,[34][35][36]. Small animal studies have shown safety and efficacy in using high powers between 50 W and 90 W with contact forces of 10-20 g and using irrigated catheters to maintain a catheter tiptissue temperature of less than 55-65°C during lesion formation 8,14,17,37.…”

« La cuisson? A point s'il vous plaît! »: Medium or well done?

“…[3][4][5] When biophysically compared with conventional RF application, HP-SD energy settings change the relationship of resistive and conductive heating during lesion formation. [3][4][5] When biophysically compared with conventional RF application, HP-SD energy settings change the relationship of resistive and conductive heating during lesion formation.…”

“…4 Due to anatomical reasons, the assessment of esophageal lesions was rightfully excluded. Therefore, the manufacturer integrated three thermocouples into the distal RF electrode and three thermocouples more proximally.…”

“…First preclinical studies of HP-SD RF applications show promising results. [3][4][5] When biophysically compared with conventional RF application, HP-SD energy settings change the relationship of resistive and conductive heating during lesion formation. The high power level increases the effect of resistive heating, whereas the proportional amount of conductive cooling decreases in parallel.…”

“…In a temperature controlled mode, the RF generator analyzes this temperature profile at a high sampling rate and automatically titrates down power when the sensed temperature exceeds a selected upper limit (60-65 • C). 4 HP-SD RF applications and their resulting lesion characteristics seem to be particularly suited for thin-walled structures, particularly the PV antrum. These power settings could contribute to a complete encirclement during PVI, by ensuring better contiguity between adjacent lesions.…”