Safety and effectiveness of an antiseptic wound cleansing and irrigation solution containing polyhexamethylene biguanide
Mark G Rippon,
Kristian Daly,
Alan A Rogers
et al.
Abstract:Objective: There is currently a wide range of cleansing and irrigation solutions available for wounds, many of which contain antimicrobial agents. The aim of this study was to assess the safety of HydroClean Solution (HARTMANN, Germany), a polyhexamethylene biguanide (PHMB)-containing irrigation solution, in a standard cytotoxicity assay, and to assess its effect in a three-dimensional (3D) full-thickness model of human skin. Method: A number of commercially available wound cleansing and irrigation solutions, … Show more
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