RuralCovidLife: Study protocol and description of the data

Stevenson, Anna J.; Huggins, Charlotte; Forbes, Alison; Hume, Jim; Fulton, Grant; Thirlwall, Claire; Miles, Janet; Fawns-Ritchie, Chloë; Campbell, Archie; Nangle, Clifford; Dawson, Rebecca; Edwards, Robin R; Flaig, Robin; Hartley, Louise; Levein, Christie; McCartney, Daniel L.; Deary, Ian J.; Hayward, Caroline; Marioni, Riccardo E.; McIntosh, Andrew M.; Sudlow, Cathie; Porteous, David J.

doi:10.12688/wellcomeopenres.17325.1

Cited by 2 publications

(4 citation statements)

References 20 publications

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“…The second was distributed directly to invited participants from Generation Scotland or CovidLife, using personal links that allowed linkage to their GS or CovidLife data. Both the general public and linked versions of the questionnaires can be seen in the Extended data 20 .…”

Section: Resultsmentioning

confidence: 99%

“…A summary of the topics assessed in the survey is shown in Table 1 . The full RuralCovidLife questionnaire is available in the Extended data 20 . The Qualtrics survey file can also be requested from the authors.…”

Section: Methodsmentioning

confidence: 99%

“…Following this, participants completed a consent form confirming their age, rural location, and consent to re-contact in the future. The consent and volunteer information sheet is available in the Extended Data 20 . After beginning the survey, participants had 14 days to complete it.…”

Section: Methodsmentioning

confidence: 99%

“…Zenodo: Extended data for “RuralCovidLife: Study protocol and description of the data”, https://doi.org/10.5281/zenodo.5589038 20 …”

Section: Data Availabilitymentioning

confidence: 99%

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RuralCovidLife: A new resource for the impact of the pandemic on rural Scotland.

et al. 2022

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RuralCovidLife is part of Generation Scotland’s CovidLife project, investigating the impact of the COVID-19 pandemic and mitigation measures on people in Scotland. The RuralCovidLife project focuses on Scotland’s rural communities, and how they have been impacted by the pandemic. During survey development, Generation Scotland consulted with people living or working in rural communities, and collaborated with a patient and public involvement and engagement (PPIE) group composed of rural community leaders. Through this consultation work, the RuralCovidLife survey was developed to assess the issues most pertinent to people in rural communities, such as mental health, employment, transport, connectivity, and local communities. Between 14th October and 30th November 2020, 3,365 participants from rural areas in Scotland took part in the survey. Participant ages ranged from 16 to 96 (mean = 58.4, standard deviation [SD] = 13.3), and the majority of the participants were female (70.5%). Over half (51.3%) had taken part in the original CovidLife survey. RuralCovidLife includes a subsample (n = 523) of participants from the Generation Scotland cohort. Pre-pandemic data on health and lifestyle, as well as biological samples, are available for these participants. These participants’ data can also be linked to past and future healthcare records, allowing analysis of retrospective and prospective health outcomes. Like Generation Scotland, RuralCovidLife is designed as a resource for researchers. RuralCovidLife data, as well as the linked Generation Scotland data, is available for use by external researchers following approval from the Generation Scotland Access Committee. RuralCovidLife can be used to investigate mental health, well-being, and behaviour in participants living in rural areas during the COVID-19 pandemic, as well as comparisons with non-rural samples. Moreover, the sub-sample with full Generation Scotland data and linkage can be used to investigate the long-term health consequences of the COVID-19 pandemic in rural communities.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…Zenodo: Extended data for “RuralCovidLife: Study protocol and description of the data”, https://doi.org/10.5281/zenodo.5589038 20 …”

Section: Data Availabilitymentioning

confidence: 99%

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RuralCovidLife: A new resource for the impact of the pandemic on rural Scotland.

et al. 2022

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Generation Scotland: an update on Scotland’s longitudinal family health study

Milbourn,

McCartney,

Richmond

et al. 2024

BMJ Open

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PurposeGeneration Scotland (GS) is a large family-based cohort study established as a longitudinal resource for research into the genetic, lifestyle and environmental determinants of physical and mental health. It comprises extensive genetic, sociodemographic and clinical data from volunteers in Scotland.ParticipantsA total of 24 084 adult participants, including 5501 families, were recruited between 2006 and 2011. Within the cohort, 59% (approximately 14 209) are women, with an average age at recruitment of 49 years. Participants completed a health questionnaire and attended an in-person clinic visit, where detailed baseline data were collected on lifestyle information, cognitive function, personality traits and mental and physical health. Genotype array data are available for 20 026 (83%) participants, and blood-based DNA methylation (DNAm) data for 18 869 (78%) participants. Linkage to routine National Health Service datasets has been possible for 93% (n=22 402) of the cohort, creating a longitudinal resource that includes primary care, hospital attendance, prescription and mortality records. Multimodal brain imaging is available in 1069 individuals.Findings to dateGS has been widely used by researchers across the world to study the genetic and environmental basis of common complex diseases. Over 350 peer-reviewed papers have been published using GS data, contributing to research areas such as ageing, cancer, cardiovascular disease and mental health. Recontact studies have built on the GS cohort to collect additional prospective data to study chronic pain, major depressive disorder and COVID-19.Future plansTo create a larger, richer, longitudinal resource, ‘Next Generation Scotland’ launched in May 2022 to expand the existing cohort by a target of 20 000 additional volunteers, now including anyone aged 12+ years. New participants complete online consent and questionnaires and provide postal saliva samples, from which genotype and salivary DNAm array data will be generated. The latest cohort information and how to access data can be found on the GS website (www.generationscotland.org).

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RuralCovidLife: Study protocol and description of the data

Cited by 2 publications

References 20 publications

RuralCovidLife: A new resource for the impact of the pandemic on rural Scotland.

RuralCovidLife: A new resource for the impact of the pandemic on rural Scotland.

Generation Scotland: an update on Scotland’s longitudinal family health study

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