Ruptured renal cyst in polycystic disease

Ravich, Lawrence; Lerman, Philip H.; Drabkin, Joel W.

doi:10.1016/0090-4295(76)90563-x

Cited by 6 publications

(3 citation statements)

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“…Occasionally subcapsular and retroperitoneal hemorrhage or hemoperitoneum may occur. 16,17 Vascular endothelial growth factor produced by the cystic epithelium promotes angiogenesis, which increases the risk of hemorrhage into cysts and gross hematuria. Symptomatic episodes probably underestimate the frequency of cyst hemorrhage because more than 90% of patients with ADPKD have cysts that are hyper-dense (on computed tomography [CT] scan) or high signal (on magnetic resonance imaging [MRI]), indicative of blood or high protein content.…”

Section: Kidney Painmentioning

confidence: 99%

Evaluation and Management of Pain in Autosomal Dominant Polycystic Kidney Disease

Hogan

Norby

2010

Advances in Chronic Kidney Disease

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Section: Kidney Painmentioning

confidence: 99%

Evaluation and Management of Pain in Autosomal Dominant Polycystic Kidney Disease

Hogan

Norby

2010

Advances in Chronic Kidney Disease

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“…Gross hematuria is present in infected cysts, cyst rupture/hemorrhage, and nephrolithias many as 43% to greater than 50% of the patients with asis that often cause crippling acute renal pain. Discussed polycystic kidney disease [26]. Hemorrhage into a cyst below are the most common etiologies of acute pain.…”

Section: Acute Pain In Adpkdmentioning

confidence: 99%

Pain management in polycystic kidney disease

Bajwa

Gupta

Warfield

et al. 2001

Kidney International

128

106

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Pain is a common complaint in patients with autosomal-dominant polycystic kidney disease, and a systematic approach is needed to differentiate the etiology of the pain and define an approach to management. A thorough history is the best clue to the multifactorial causes of the pain, superimposed upon an understanding of the complex innervation network that supplies the kidneys. The appropriate use of diagnostic radiology (especially MRI) will assist in differentiating the mechanical low back pain caused by cyst enlargement, cyst rupture and cyst infection. Also, the increased incidence of uric acid nephrolithiasis as a factor in producing renal colic must be considered when evaluating acute pain in the population at risk. MRI is not a good technique to detect renal calculi, a frequent cause of pain in polycystic kidney disease. If stone disease is a possibility, then abdominal CT scan and/or ultrasound should be the method of radiologic investigation. Pain management is generally not approached in a systematic way in clinical practice because most physicians lack training in the principles of pain management. The first impulse to give narcotics for pain relief must be avoided. Since chronic pain cannot be "cured," an approach must include techniques that allow the patient to adapt to chronic pain so as to limit interference with their life style. A detailed stepwise approach for acute and chronic pain strategies for the patient with autosomal dominant polycystic kidney disease is outlined.

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“…Approximately 42% to greater than 50% of ADPKD patients have experienced at least one episode of gross hematuria (Rovitch et al 1976;Gabow, Duley and Johnson 1992). In 20% of ADPKD patients gross hematuria was the initial diagnostic clue.…”

Section: Acute Painmentioning

confidence: 99%

Developments in the management of autosomal dominant polycystic kidney disease

Schrier¹

2008

TCRM

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Abstract:Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent life-threatening, hereditary disease. ADPKD is more common than sickle cell anemia, cystic fi brosis, muscular dystrophy, hemophilia, Down's syndrome, and Huntington's disease combined. ADPKD is a multisystemic disorder characterized by the progressive development of renal cysts and marked renal enlargement. Structural and functional renal deterioration occurs in ADPKD patients and is the fourth leading cause of end-stage renal disease (ESRD) in adults. Aside from the renal manifestations, extrarenal structural abnormalities, such as liver cysts, cardiovascular abnormalities, and intracranial aneurysms may lead to morbidity and mortality. Recent studies have identifi ed prognostic factors for progressive renal impairment including gender, race, age, proteinuria, hematuria, hypertension and increased left ventricular mass index (LVMI). Early diagnosis and better understanding of the pathophysiology of the disease provides the opportunity to aggressivly treat hypertension with renin-angiotensin-aldosterone system inhibitors and thereby potentially reduce LVMI, prevent cardiovascular morbidity and mortality and slow progression of the renal disease.

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Ruptured renal cyst in polycystic disease

Cited by 6 publications

References 0 publications

Evaluation and Management of Pain in Autosomal Dominant Polycystic Kidney Disease

Evaluation and Management of Pain in Autosomal Dominant Polycystic Kidney Disease

Pain management in polycystic kidney disease

Developments in the management of autosomal dominant polycystic kidney disease

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