Ruptured Aneurysm of the Subclavian Artery in a Patient With von Recklinghausen's Disease

Clinical and genetic aspects of neurofibromatosis 1

“…NF1 vasculopathy involving the arteries of the heart or brain or other major arteries can have serious or even fatal consequences. 46,[51][52][53][54] Cerebrovascular abnormalities may present in children with NF1 as stenoses or occlusions of the internal carotid, middle cerebral, or anterior cerebral artery. Small telangiectatic vessels form around the stenotic area and appear as a "puff of smoke" (moyamoya) on cerebral angiography.…”

Ruptured brachial artery aneurysm in a patient with type 1 neurofibromatosis

“…4 Despite the low incidence, disrupted NF1 vasculopathy can lead to fatal massive hemorrhage. 12,13 Although the true incidence of arterial aneurysms associated with NF1 is uncertain, arterial aneurysms in the upper extremity (axillary, brachial, radial artery aneurysm) may be the least common. 5 Three patients with NF1 suffering from ruptured brachial artery were reported (Table); 6-8 two required resection of the aneurysms and the brachial artery and vein after ligation of the vessels, 6,8 while the third required a transhumeral amputation after an unsuccessful attempt to reconstruct a ruptured aneurysm with a vein graft.…”

Transcatheter Embolization of a Ruptured Internal Pudendal Artery Pseudoaneurysm in a Patient with Neurofibromatosis Type 1

“…Fibrous dysplasia or fibrosis of the vessel wall complicated with myocyte atrophy or sacculated aneurysm are its common pathological features. However, NF-1 is remarkable for its association with occlusive or aneurismal arterial disease affecting predominantly the renal arteries and less often the abdominal aorta, and mesenteric and peripheral arteries (4). …”