Routine evaluation of left ventricular function using CZT-SPECT, with low injected activities and limited recording times

Claudin, Marine; Imbert, Laëtitia; Djaballah, W.; Véran, Nicolas; Poussier, Sylvain; Roch, Véronique; Perrin, M.; Verger, Antoine; Boutley, Henri; Karcher, Gilles; Marie, Pierre-Yves

doi:10.1007/s12350-016-0615-z

Cited by 18 publications

(24 citation statements)

References 23 publications

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“…The study patients were prospectively selected if, first, they had been routinely referred to our department for a single-day stress-first 99m Tc-sestamibi SPECT protocol performed with a high-sensitivity CZT camera (D.SPECT) (15,16); second, resting SPECT was subsequently indicated on the basis of the initial stress SPECT images (15); third, they were in sinus rhythm, without significant arrhythmia and left bundle branch block; and fourth, they agreed to participate and to sign the informed consent form.…”

Section: Study Populationmentioning

confidence: 99%

“…The stress tests were performed as described previously (15,16), with exercise performed in the upright position on a bicycle ergometer or with a pharmacologic test conducted with dipyridamole (0.56 mgÁkg 21 ) or regadenoson (400 mg).…”

Section: Stress Tests and Tracer Injectionmentioning

confidence: 99%

“…As already detailed elsewhere (15,16), each projection was set to target the recording of approximately 500 myocardial kilocounts, leading to recording times of no more than 10 min for stress acquisitions and almost 4 min for rest acquisitions.…”

Section: Acquisition and Reconstruction Of Dspect Imagesmentioning

confidence: 99%

“…Image reconstruction was conducted using the parameters already described elsewhere for SPECT (15) and gated SPECT (16).…”

Section: Acquisition and Reconstruction Of Dspect Imagesmentioning

confidence: 99%

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Assessment of Myocardial CZT SPECT Recording in a Forward-Leaning Bikerlike Position

Perrin¹,

Roch²,

Claudin³

et al. 2018

J Nucl Med

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This prospective randomized study assessed myocardial perfusion imaging with the high-sensitivity D.SPECT cadmium-zinc-telluride camera in a forward-leaning bikerlike position, which may potentially lower diaphragmatic attenuation and reduce breathing-related cardiac motion, in a manner comparable to the prone position proposed with other SPECT cameras. Methods: Patients referred for a stress-rest 99m Tc-sestamibi protocol and positioned in the biker position, with the chest leaning forward on the D.SPECT camera-head at 35°from vertical, had an additional resting D.SPECT recording in the supine position (n 5 40) or in the sitting position with the back rearward at 30°from vertical (n 5 40). Segments with attenuation artifacts were defined as those with less than 65% uptake but with strictly normal contractility at gated SPECT and no defect reversibility from stress images. Results: The biker position was associated with lower heart-to-detector distances than the supine or sitting positions (both P , 0.001); lower cardiac motion amplitudes, assessed on panograms, than the supine position (P , 0.001); and fewer segments with attenuation artifacts than the supine position (on average, 1.10 ± 1.01 vs. 1.90 ± 1.74, P 5 0.010) or the sitting position (0.75 ± 0.93 vs. 1.38 ± 1.60, P 5 0.011). Conclusion: Myocardial perfusion images from D.SPECT are enhanced for patients positioned in a forward-leaning bikerlike position comparatively to sitting or supine positions, with a notably lower rate of attenuation artifacts.

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Section: Study Populationmentioning

confidence: 99%

Section: Stress Tests and Tracer Injectionmentioning

confidence: 99%

Section: Acquisition and Reconstruction Of Dspect Imagesmentioning

confidence: 99%

“…Image reconstruction was conducted using the parameters already described elsewhere for SPECT (15) and gated SPECT (16).…”

Section: Acquisition and Reconstruction Of Dspect Imagesmentioning

confidence: 99%

See 2 more Smart Citations

Assessment of Myocardial CZT SPECT Recording in a Forward-Leaning Bikerlike Position

Perrin¹,

Roch²,

Claudin³

et al. 2018

J Nucl Med

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“…Information on LV systolic function provided by gated-SPECT may also be useful in this setting, keeping in mind that this assessment may now be obtained with very low radiation doses on recent CZT cameras. 13 In particular, in a still ongoing multicenter prospective trial, end-systolic volume, determined with gated-SPECT, was found to provide strong predictive information on the risk of cardiac death, in addition to information provided by the extent of stress perfusion abnormalities. 14 In addition to the above, very promising gated-SPECT results have been provided to date by phase parameters reflecting mechanical LV dyssynchrony with strong relationships with the prognosis of CKD patients, independently of myocardial perfusion and LV ejection fraction.…”

mentioning

confidence: 99%

Stress myocardial perfusion gated-SPECT imaging in advanced chronic kidney disease

Marie

Rossignol

2019

Journal of Nuclear Cardiology

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Cardiovascular death is a leading cause of death in patients with chronic kidney disease (CKD), while the risk of cardiovascular mortality, adjusted for traditional cardiovascular risk factors and albuminuria, is linearly and negatively correlated with renal function. 1 In particular, cardiovascular mortality in CKD patients who are on dialysis is 10 to 20 times higher than in the general population. 2,3 This increased cardiovascular risk primarily concerns coronary artery disease (CAD), 4 with CKD patients exhibiting high prevalences of traditional cardiovascular risk factors (advanced age, hypertension, diabetes, dyslipidemia) as well as certain uremia-specific risk factors. 5 It should also be borne in mind that the atherosclerotic process in CKD patients can remain highly active even after renal transplantation, with hypertension, hyperlipidemia, and hyperglycemia being further facilitated by immunosuppressant therapy (corticosteroids, calcineurin inhibitors). Indeed, the mortality of CKD patients remains of cardiovascular origin in 35% to 50% of cases after transplantation. 4

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The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

Bednárová

Kincl

Kamínek

et al. 2019

Int J Cardiovasc Imaging

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Routine evaluation of left ventricular function using CZT-SPECT, with low injected activities and limited recording times

Abstract: LV function, assessed on a CZT camera with low injected activities and limited recording times, correlates well with the reference assessment from cardiac MRI.

Cited by 18 publications

References 23 publications

Assessment of Myocardial CZT SPECT Recording in a Forward-Leaning Bikerlike Position

Assessment of Myocardial CZT SPECT Recording in a Forward-Leaning Bikerlike Position

Stress myocardial perfusion gated-SPECT imaging in advanced chronic kidney disease

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

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