Ropivacaine 0.25% Versus Bupivacaine 0.25% for Continuous Epidural Analgesia in Labor

Stienstra, Rudolf; Jonker, Tim A.; Bourdrez, Petra; Kuijpers, Johan C.; Kleef, Jack W. van; Lundberg, Ulrika

doi:10.1213/00000539-199502000-00014

Cited by 7 publications

(6 citation statements)

References 12 publications

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“…The results of the present study are better than that of Stienstra et al (58% excellent for bupivacaine and for ropivacaine excellent in 64.5% cases and satisfactory in 29% cases) [5], and Muir et al (52.94% excellent analgesia for bupivacaine and excellent analgesia in 82.353% cases of ropivacaine) [6]. The reason may be the use of bupivacaine only without the addition of opioids.…”

Section: Discussioncontrasting

confidence: 67%

Comparison of 0.1% Ropivacaine-Fentanyl with 0.1% Bupivacaine-Fentanyl Epidurally for Labour Analgesia

Chora

Hussain

2014

Advances in Anesthesiology

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Ropivacaine is an alternative to epidural bupivacaine, with greater selectivity for sensory fibres than motor fibres, thus producing less motor blockade as compared to bupivacaine. The purpose of this study was to evaluate the efficacy of Ropivacaine 0.1% when administered epidurally for the relief of labour pain and to compare it with 0.1% bupivacaine, conducted at Rajindra Hospital Patiala, Baba Farid University of Health and Sciences, on 20 parturients after ethical approval from the institutional review board and obtaining written informed consent. Participants were randomly allocated to the two groups (bupivacaine 0.1% (Sensorcaine) + fentanyl 20 g versus ropivacaine 0.1% (Ropin) + fentanyl 20 g). It was observed that ropivacaine 0.1% and bupivacaine 0.1%, with fentanyl 20 g/mL, produced equivalent analgesia for labour. There were no statistically significant differences in the amount of local anaesthetic used, pain scores, sensory levels, motor blockade, labour duration, mode of delivery, and side effects or patient satisfaction amongst the two local anaesthetics using the intermittent top-up technique. We conclude that the combinations of ropivacaine or bupivacaine with fentanyl achieve equally effective and excellent labour analgesia with no motor blockade and without jeopardizing the safety of the mother and foetus and, hence, are recommended for labour analgesia.

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Section: Discussioncontrasting

confidence: 67%

Comparison of 0.1% Ropivacaine-Fentanyl with 0.1% Bupivacaine-Fentanyl Epidurally for Labour Analgesia

Chora

Hussain

2014

Advances in Anesthesiology

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“…12 The continuous epidural infusion of 0.25% ropivacaine or 0.25% bupivacaine were equally effective in providing pain relief during labor. 13 Ropivacaine and bupivacaine, when compared using similar concentrations, were equally effective in providing brachial plexus anesthesia. 14,15 It has been concluded that on a dose for dose basis, ropivacaine offers comparable surgical analgesia, but with slower onset, lesser potency, shorter duration, and weaker motor blockade than bupivacaine.…”

Section: Discussionmentioning

confidence: 96%

Pain on intramuscular injection of bupivacaine, ropivacaine, with and without dexamethasone

Krishnan

2000

Regional Anesthesia and Pain Medicine

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“…after a bolus dose of 10ml of same concentration, there was effective pain relief in labour and no difference in the mode of delivery and neonatal outcome. (16) α2-Receptors Agonists They include centrally-acting α2-adrenergic receptor agonists, clonidine and dexmedetomidine, which have potent sedative and opioid analgesic-sparing properties. They can reduce the intravenous and volatile anesthetic requirements as well as the postoperative opioid requirement.…”

Section: Peripheral Nerve Blocksmentioning

confidence: 99%

Comparative Study of Epidural Ropivacaine With Dexmedetomidine , Ropivacaine With Clonidine and Ropivacaine Alone for Perioperative Analgesia in Abdominal Hysterectomy

Satheedevi¹,

Rasikapriya²,

Chithra³

2015

jemds

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Regional anesthesia is widely used for abdominal hysterectomies. It is divided into spinal and epidural anaesthesia. Epidural anesthesia has got the advantage of extending the period of anesthesia to post-operative analgesia. We can use various pharmacological agents as adjuvants, which prolong the duration of action of local anesthetics. They include opiods, alpha 2 agonists like clonidine and dexmedetomidine. In this we studied the efficacy of local anesthetic agent -ropivacaine alone, ropivacaine with clonidine and ropivacaine with dexmedetomidine for epidural block. Present study showed that Epidural Dexmedetomidine and clonidine have synergistic action in combination with epidural ropivacaine resulting in smooth and prolonged postoperative analgesia and sedation. Group RD (Ropivacaine and Dexmedetomidine) had significant difference in comparison of postoperative block characteristics, such as time of two segment regression, time to Bromage scale 1, time of regression to S1 dermatome and time of first epidural top up than group RC and R. (Ropivacaine with clonidine and Ropivacaine alone). Thus epidural dexmedetomidine is a better neuraxial adjuvant in combination with epidural ropivacaine in producing prolonged analgesia and better sedation for abdominal hysterectomy.

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Ropivacaine 0.25% Versus Bupivacaine 0.25% for Continuous Epidural Analgesia in Labor

Cited by 7 publications

References 12 publications

Comparison of 0.1% Ropivacaine-Fentanyl with 0.1% Bupivacaine-Fentanyl Epidurally for Labour Analgesia

Comparison of 0.1% Ropivacaine-Fentanyl with 0.1% Bupivacaine-Fentanyl Epidurally for Labour Analgesia

Pain on intramuscular injection of bupivacaine, ropivacaine, with and without dexamethasone

Comparative Study of Epidural Ropivacaine With Dexmedetomidine , Ropivacaine With Clonidine and Ropivacaine Alone for Perioperative Analgesia in Abdominal Hysterectomy

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