volume 93, issue 0, P2-P-198 2020
DOI: 10.1254/jpssuppl.93.0_2-p-198
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Abstract: Peripheral hydrogen sulfide (H 2 S) is reported as an endogenous relaxation factor in the bladder, while in the central nervous system, roles of H 2 S in regulation of micturition is unclear. In this study, therefore, we examined effects of centrally administered GYY4137 (GYY, H 2 S donor) or AOAA (H 2 S synthesis inhibitor), on the micturition reflex in urethane-anesthetized (0.8 g/kg, ip) male Wistar rats. A catheter was inserted into the bladder to perform cystometrograms (CMG). CMG was started 2 h after th…

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