2013
DOI: 10.2754/avb201382030331
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Abstract: Investigation of the effect of α 1 -adrenergic receptor subtypes on the contraction of the abdominal aorta will allow for more effective treatment of hypertension by use of selective antagonists. The aim of the study was to evaluate the participation of α 1 -adrenergic receptor subtypes in the contractility of the aortic smooth muscle cells in rabbits. The in vitro experiments were performed in isolated tissue preparations from 30 adult female New Zealand rabbits. The abdominal aortic sections were placed in o… Show more

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Cited by 2 publications
(1 citation statement)
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“…This reciprocal effect is unexpected. Gnus et al 18) demonstrated in an in vitro study that 1A receptors played a major role in the contraction of the rabbit aortic wall. The non-selective blocker phentolamine may dilate the arteries through the 1-adrenergic receptor 12,13) .…”
Section: Discussionmentioning
confidence: 99%
“…This reciprocal effect is unexpected. Gnus et al 18) demonstrated in an in vitro study that 1A receptors played a major role in the contraction of the rabbit aortic wall. The non-selective blocker phentolamine may dilate the arteries through the 1-adrenergic receptor 12,13) .…”
Section: Discussionmentioning
confidence: 99%