Current Opinion in Hematology volume 17, issue 4, P294-299 2010 DOI: 10.1097/moh.0b013e328338c439 View full text
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Jan J Schuringa, Edo Vellenga

Abstract: Understanding molecular mechanisms by which BMI1 affects stem cell fate will increase our insights into the biology of hematopoietic stem cells and will also aid in understanding the process of leukemic transformation and ultimately in the identification of drugable targets that might facilitate the eradication of leukemic stem cells.