Role of T Cells in Viral and Immune-mediated Myocarditis
Chunyan Cheng,
Anna Baritussio,
Andrea Silvio Giordani
et al.
Abstract:Myocarditis is characterized by inflammatory cell infiltration into the myocardium and a high risk of deteriorating cardiac function with a heterogeneous etiology. Both viral- and myosin-induced myocarditis experimental models are used to mimic myocarditis in humans. Here, coxsackie virus B3 (CVB3)-induced and non-virus-induced myocarditis models and data obtained in clinical studies were reviewed. Experimental murine myocarditis following immunization with α-myosin together with complete Freund adjuvant repre… Show more
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