Role of oral tramadol 50 mg in reducing pain associated with outpatient hysteroscopy: A randomised double‐blind placebo‐controlled trial

Hassan, AbdelGany; Haggag, Hisham

doi:10.1111/ajo.12431

Cited by 18 publications

(25 citation statements)

References 18 publications

(20 reference statements)

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“…After the initial title and abstract screening, the full‐texts of 100 potentially eligible citations were retrieved for evaluation. Finally, 39 RCT (Women n = 3964) were included in the present systematic review and NMA. Figure shows the PRISMA flowchart.…”

Section: Resultsmentioning

confidence: 99%

Evaluation and ranking of different interventions for pain relief during outpatient hysteroscopy: A systematic review and network meta‐analysis

Ghamry

Samy

Abdelhakim

et al. 2020

J of Obstet and Gynaecol

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Section: Resultsmentioning

confidence: 99%

Evaluation and ranking of different interventions for pain relief during outpatient hysteroscopy: A systematic review and network meta‐analysis

Ghamry

Samy

Abdelhakim

et al. 2020

J of Obstet and Gynaecol

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“…Pain is sometimes a problem after hysteroscopy [ 2 ] and conservative treatment with opioids often gives adequate pain relief [ 3 ]. However, opioids have serious side effects, such as sedation, nausea and respiratory depression [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of high-frequency, high-intensity transcutaneous electrical nerve stimulation versus intravenous opioids for pain relief after hysteroscopy: a randomized controlled study

et al. 2020

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Objective To compare the time spent in the Post-Anesthesia Care Unit (PACU) and the pain-relieving effects of treatment with high-frequency, high-intensity transcutaneous electrical nerve stimulation (TENS) or intravenous (IV) opioids after hysteroscopy. Methods All patients who postoperatively reported a visual analogue scale (VAS) pain score of ≥3 were included in the study. TENS treatment was given with a stimulus intensity between 40 and 60 mA for 1 minute and repeated once if there was insufficient pain relief. In the opioid group, a fractionated dose of 5 mg morphine was administered. If the patient reported insufficient pain relief after the assigned treatment, the patient was reassigned to the other treatment group. Results Seventy-four women were randomized to TENS (n=38) or IV opioids (n=36) for treatment. Both groups reported significant pain relief after discharge from the PACU, with a decrease of VAS scores from 5.6 to 1.4 in the TENS group ( P <0.001) and 5.1 to 1.3 in the opioid group ( P <0.001). There were no significant differences between the groups. When only the responders in both groups, i.e., patients with VAS scores of <3 on respectively assigned treatments, were compared, the TENS responders (n=22) were found to have spent a significantly shorter time in the PACU (91 vs. 69 minutes, P =0.013) compared to the opioid responders (n=20). Conclusion Using TENS as first line of pain relief may reduce the need for postoperative opioids. In addition, TENS appears preferable as the first line of treatment due to its association with a shorter time spent in the PACU if the patient responds to the treatment. Trial Registration Västra Götalandsregionen Identifier: 211261

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“…Initially, hysteroscopy was performed in the operative room (OR), mostly in general anesthesia. Since that time, several different techniques of analgesia have been tested, including local anesthesia, oral or vaginal premedication or intrauterine analgesia [3][4][5]. The greatest breakthrough was the moment of introduc-ing an office setting for hysteroscopy where no anesthesia nor analgesia was used.…”

Section: Introductionmentioning

confidence: 99%

Is every patient eligible to have an office hysteroscopy? A retrospective analysis of 1301 procedures.

Biela¹,

Doniec²,

Szafarowska³

et al. 2019

Videosurgery and Other Miniinvasive Techniques

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Introduction: Hysteroscopy is the gold standard for diagnosis and treatment of uterine pathologies. The office setting seems to be safe, reducing the anesthesia risks and also decreasing the overall costs of the procedure. Recent literature suggests that hysteroscopy performed without anesthesia may not be as painless as it was previously considered. Moreover, not every patient can be referred for a hysteroscopy in an office setting. Aim: To analyze the factors correlated with a successful hysteroscopy in an office setting. Material and methods: We analyzed the documentation of 1301 patients who underwent hysteroscopy at our department in the period 2013-2016. The impact of the type of the procedure and the various demographic factors on the need for general anesthesia was assessed. Results: Almost 80% of all hysteroscopies were performed without analgesia in an office setting. The remaining patients underwent a hysteroscopy in general anesthesia. The key aspect for successful office hysteroscopy is the scope of the performed surgery. Over 91% of diagnostic hysteroscopies have been done without analgesia, but only about 30% of extensive endometrial scratching procedures were performed in an office setting. A previous vaginal delivery increases the chances for a successful office hysteroscopy by about 21%, and in the case of diagnostic procedures, multiparous patients were at an about 79% lower risk of analgesia necessity. Conclusions: It is possible to perform nearly all diagnostic hysteroscopies in an office setting. In the case of operative hysteroscopy, the most crucial factor is the scope of the procedure.

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Role of oral tramadol 50 mg in reducing pain associated with outpatient hysteroscopy: A randomised double‐blind placebo‐controlled trial

Abstract: Oral administration of tramadol 50 mg before hysteroscopy reduces the pain evoked by the procedure and the drug was well tolerated by women.

Cited by 18 publications

References 18 publications

Evaluation and ranking of different interventions for pain relief during outpatient hysteroscopy: A systematic review and network meta‐analysis

Evaluation and ranking of different interventions for pain relief during outpatient hysteroscopy: A systematic review and network meta‐analysis

Effects of high-frequency, high-intensity transcutaneous electrical nerve stimulation versus intravenous opioids for pain relief after hysteroscopy: a randomized controlled study

Is every patient eligible to have an office hysteroscopy? A retrospective analysis of 1301 procedures.

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