Role of Obesity in Recurrent Vulvovaginal Symptoms and Disease

Powell, Ann‐Marie; Sarria, Isabella; Goje, Oluwatosin

doi:10.1007/s11908-022-00793-2

Cited by 2 publications

(2 citation statements)

References 46 publications

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“…This association may be attributed to chronic inflammation resulting from induced immune dysfunction. However, the relationship between weight, height, BMI, and chronic vulvar discomfort is not fully understood [24,25]. It is important to note that these findings are not consistently reported in all studies, and further research is needed to establish a clear association, if any, between weight, height, BMI, and chronic vulvar discomfort [26,27].…”

Section: Introductionmentioning

confidence: 99%

Basic Characteristics and Demographic Data in Patients with Chronic Vulvar Discomfort: A Detailed Analysis of DATRIV Study

Harni,

Babic,

Hadzavdic

et al. 2024

JGO

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This study aims to provide a descriptive analysis of the essential characteristics and demographic profiles, including age, weight, height, body mass index, marital status, and educational background in patients with chronic vulvar discomfort. The data were collected from the study DATRIV (Diagnostic Accuracy of Three Rings Vulvoscopy), which included 328 participants divided into four groups: normal vulva, impaired vulvar skin, primary vulvar distress/vulvodynia, and secondary discomfort caused by vulvar dermatoses. The clinical data collected from the study questionnaire were analyzed using statistical software such as StatSoft (Dell, Austin, TX, USA), Statistica 12 (TIBCO®, Palo Alto, CA, USA), and SPSS 20 (IBM, Armonk, NY, USA). The study was conducted with the approval of the Institutional Review Board of Polyclinic Harni, and all participants provided written informed consent. The findings from the DATRIV study shed light on several important aspects of chronic vulvar discomfort. They offered valuable insights into the demographic and reproductive characteristics of patients with chronic vulvar pain, specifically vulvar dermatosis. The study revealed that patients with vulvar dermatosis tended to be older, with a peak incidence in the 45-65 age range. They also had higher weight and BMI compared to other groups. There was a significant difference in the proportion of patients of reproductive age between the vulvar dermatosis group and other groups. Additionally, the vulvar dermatosis group had higher rates of marriage, births, and abortions and lower educational levels. The study's limitations included lacking patients younger than 16 years. Future research should aim to include a broader age range, including pediatric populations, to gain a more comprehensive understanding of vulvar dermatosis across different age groups. Further investigation is needed to uncover the underlying mechanisms and establish causal relationships, enhancing diagnosis, treatment, and support for individuals affected by vulvar dermatosis.

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Section: Introductionmentioning

confidence: 99%

Basic Characteristics and Demographic Data in Patients with Chronic Vulvar Discomfort: A Detailed Analysis of DATRIV Study

Harni,

Babic,

Hadzavdic

et al. 2024

JGO

View full text Add to dashboard Cite

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“…While it is generally caused by infection, especially after menopause, may be the consequence of hormonal imbalance [2]. Typical symptoms are: burning, pruritus, dyspareunia, pain, leucoxanthorrhea, and vaginal discharge [3]. There are different types of vaginitis, which have other causes, symptoms, and treatments.…”

Section: Introductionmentioning

confidence: 99%

Rigenase® and Polyhexanide Combination in a Hydrogel Formulation for the Treatment of Vaginosis Symptoms: The PMCF Survey

2023

Gynecol Obstet Open Acc

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Background and Objectives: Signs and symptoms of vulvovaginitis, especially when recurrent, have a significant impact on women's quality of life. The aim of this study was to evaluate the efficacy of a novel vaginal hydrogel (Fitostimoline ® Septagel) composed of wheat extracts (Rigenase ® ) and polyhexanide in reducing vulvovaginitis symptomatology. Materials and Methods: A nationwide analysis of a national survey performed on 1402 patients across Italy. Pre-and postmenopausal women with suspicion of vulvovaginitis due to at least four of the following symptoms (leucoxanthorrhea, bad odor from genitalia, vulvovaginal dryness, petechiae, burning, and pruritus) while waiting for microbiological swab analysis were included and treated with one hydrogel application every 3 days for 1 week. Primary endpoint was the complete resolution of the symptomatology by the hydrogel application. Results: Overall, 1402 (722 of fertile age and 680 in post-menopause) women were included in this study. At the 28th follow-up examination, complete resolution of symptomatology was achieved in 1380/1402 (95%; p<0.001) within 12.8+-7 and 14 +-8 days for those of fertile age and in post menopause, respectively (p=0.342). All of the evaluated symptoms were significantly reduced after treatment (p=0.001) without differences according to the patient's menopausal status. No patient reported side effects, adverse reactions, or discontinued therapy and the product was found to be in compliance with its indication and application. Conclusions: This pilot study showed that the hydrogel based on Rigenase ® (wheat extract) and polyhexanide could be a promising treatment for the relief of vulvovaginitis symptoms.

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Role of Obesity in Recurrent Vulvovaginal Symptoms and Disease

Cited by 2 publications

References 46 publications

Basic Characteristics and Demographic Data in Patients with Chronic Vulvar Discomfort: A Detailed Analysis of DATRIV Study

Basic Characteristics and Demographic Data in Patients with Chronic Vulvar Discomfort: A Detailed Analysis of DATRIV Study

Rigenase® and Polyhexanide Combination in a Hydrogel Formulation for the Treatment of Vaginosis Symptoms: The PMCF Survey

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