Role of nutrition on anemia in elderly

Bianchi, Vittorio Emanuele

doi:10.1016/j.clnesp.2015.09.003

Cited by 49 publications

(55 citation statements)

References 152 publications

(55 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Taking into account that critical care patients and dialysis patients (Singer et al, 2008;Berger and Oudemans-Van Straaten, 2015) are often vitamin C deficient, there is potentially a chance of improving iron status by correcting vitamin C deficiency. Bianchi (2016), in his review from 2016, concludes that adequate nutrition could and should be used in the elderly in order to prevent IDA and if coupled with exercise it should reduce the rates of mortality and improve overall wellbeing. Bianchi points out that inadequate intake of protein followed by malnutrition and potentially anorexia triggers systemic inflammation, immunodeficiency disorders and anemia.…”

Section: Iron Status and Dietmentioning

confidence: 99%

“…In the 2013 review by Bianchi et al (2016) it was hypothesized that anemia in the elderly, when present in a situation of iron sufficiency, stems from a mix of comorbidities and inflammatory state. Those conditions are either impeding haematopoiesis by limiting iron through IL-6 and thus hepcidin increase or through TNF-α pathways resulting in erythropoietin (EPO) resistance (Bianchi, 2013).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Iron status in the elderly: A review of recent evidence

Wawer

Jennings

Fairweather-Tait

2018

Mechanisms of Ageing and Development

View full text Add to dashboard Buy / Rent full text

A comprehensive literature review of iron status in the elderly was undertaken in order to update a previous review (Fairweather-Tait et al, 2014); 138 summarised papers describe research on the magnitude of the problem, aetiology and age-related physiological changes that may affect iron status, novel strategies for assessing iron status with concurrent health conditions, hepcidin, lifestyle factors, iron supplements, iron status and health outcomes (bone mineral density, frailty, inflammatory bowel disease, kidney failure, cancer, cardiovascular, and neurodegenerative diseases). Each section of this review concludes with key points from the relevant papers. The overall findings were that disturbed iron metabolism plays a major role in a large number of conditions associated with old age. Correction of iron deficiency/overload may improve disease prognosis, but diagnosis of iron deficiency requires appropriate cut-offs for biomarkers of iron status in elderly men and women to be agreed. Iron deficiency (with or without anemia), anemia of inflammation, and anemia of chronic disease are all widespread in the elderly and, once identified, should be investigated further as they are often indicative of underlying disease. Management options should be reviewed and updated, and novel therapies, which show potential for treating anemia of inflammation or chronic disease, should be considered.

show abstract

Section: Iron Status and Dietmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Iron status in the elderly: A review of recent evidence

Wawer

Jennings

Fairweather-Tait

2018

Mechanisms of Ageing and Development

View full text Add to dashboard Buy / Rent full text

show abstract

“…Around one-third of anemia is nutritional anemia mainly due to calorie and protein restriction, iron, Vitamin B 12 , and folic deficiency [23]. Our study also revealed Vitamin B 12 deficiency among 33.33% of elderly with anemia.…”

Section: Data Of 1770 Elderly Individuals Aged 60 Years and Older Eldmentioning

confidence: 53%

Anemia and Vitamin B12 Deficiency in Elderly.

Gonmei

Dwivedi

Toteja

et al. 2018

Asian J Pharm Clin Res

View full text Add to dashboard Buy / Rent full text

Objective: The present study was carried out to assess the prevalence of anemia, vitamin B 12 deficiency and hyperhomocysteinemia among elderly in slums of West Delhi. Methods:A cross-sectional study was carried out among 234 elderly aged 60 and above in slums of West Delhi. 5 ml blood was collected from 116 elderly and was analyzed for hemoglobin, Vitamin B 12 and homocysteine. Anemia was defined as hemoglobin <130 g/L and <120 g/l for male and female, respectively, Vitamin B 12 deficiency as serum Vitamin B 12 <203 pg/ml and hyperhomocysteinemia as serum homocysteine >15 µmol/l. Results:The overall prevalence of anemia, Vitamin B 12 deficiency, and hyperhomocysteinemia among elderly was 57.76%, 36.36%, and 57.57%, respectively. Among anemic elderly, 33.33% and 64.15% had Vitamin B 12 deficiency and hyperhomocysteinemia, respectively. Conclusion:More than half of the elderly population was anemic, while one-third was having Vitamin B 12 deficiency.

show abstract

“…However, many reports also showed that anemia in older persons is related to the presence of underlying health conditions and is therefore associated with high mortality and morbidity. Furthermore, most people with anemia have been shown to have nutritional deficiency, but the etiology is unknown in one-third of anemia cases [3,26]. This unexplained category of anemia includes aging-related clonal hematopoiesis (ARCH), idiopathic cytopenia of undetermined significance (ICUS), and pre-myelodysplastic syndrome (MDS); these conditions are associated with a low but potential risk of hematologic malignancy [5,6,27].…”

Section: Discussionmentioning

confidence: 99%

High Anemia Prevalence in Korean Older Adults, an Urgent Healthcare Problem: 2007-2016 KNHANES

Chueh

Jung

Shim

et al. 2020

Preprint

View full text Add to dashboard Buy / Rent full text

BACKGROUND: Anemia is associated with high morbidity and mortality in older people. However, anemia in older individuals is not fully understood, and national data on the prevalence and characteristics of anemia in Korean older people are lacking. This study aimed to evaluate the prevalence and characteristics of anemia in older adults using data from the Korea National Health and Nutrition Examination Survey (KNHANES) , which is the nation-wide cross-sectional epidemiological study conducted by Korean Ministry of Health and Welfare. METHODS: Data from the total of 62,825 participants of the 2007-2016 KNHANES were merged and analyzed to investigate differences in participant characteristics and potential risk factors for anemia. RESULTS: The prevalence of anemia was higher in the population aged ≥65 years (older adults) than in the younger population. Anemia was also more prevalent among females than among males, but the difference was not statistically significant in people aged >85 years. Being underweight, receiving a social allowance, living alone, and having comorbidities such as hypertension, arthritis, diabetes mellitus (DM), cardiovascular disease (CVD), stroke, cancer, and chronic renal failure (CRF) were more prevalent in older adults with anemia than in the group without anemia. In the univariate and multivariate analyses, older age, female sex, underweight, and comorbidities including arthritis, DM, CVD, stroke, cancer, and CRF were associated with an increased risk of anemia. Furthermore, the prevalence data were significantly higher in this study than in previous studies. CONCLUSIONS: This study revealed that age, female sex, underweight, and the presence of comorbidities such as arthritis, DM, CVD, stroke, cancer, and CRF were associated with an increased risk of anemia in Korean older adults. Our findings may be useful in developing interventions and programs aimed at healthy aging. Further study on causal relationships between anemia and other variables in the older population is necessary.

show abstract

Role of nutrition on anemia in elderly

Cited by 49 publications

References 152 publications

Iron status in the elderly: A review of recent evidence

Iron status in the elderly: A review of recent evidence

Anemia and Vitamin B12 Deficiency in Elderly.

High Anemia Prevalence in Korean Older Adults, an Urgent Healthcare Problem: 2007-2016 KNHANES

Contact Info

Product

Resources

About