2020
DOI: 10.7759/cureus.9709
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Abstract: A pineal parenchymal tumor of intermediate differentiation (PPID) is a rare entity, and optimal treatment is still unclear. Combined multimodality treatment should be considered in PPID due to high recurrence rates. Gross total resection is the first choice of treatment, however, it may not be feasible in every case due to location. Stereotactic radiosurgery (SRS) can be considered for the treatment of primary and recurrent disease, as it enables us to deliver a high radiation dose to the target while minimizi… Show more

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Cited by 2 publications
(2 citation statements)
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References 21 publications
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“…PPTIDs have a long-documented history of leptomeningeal spread and dissemination after local-only therapies (ie, local RT or surgery), requiring salvage CSI for treatment to stabilize or cure disease. 14 , 15 …”
Section: Literature Review/discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…PPTIDs have a long-documented history of leptomeningeal spread and dissemination after local-only therapies (ie, local RT or surgery), requiring salvage CSI for treatment to stabilize or cure disease. 14 , 15 …”
Section: Literature Review/discussionmentioning
confidence: 99%
“…PPTIDs have a long-documented history of leptomeningeal spread and dissemination after localonly therapies (ie, local RT or surgery), requiring salvage CSI for treatment to stabilize or cure disease. 14,15 In another study, CSI was administered to 2 patients who presented with disseminated disease and underwent biopsy only, while the other 3 patients without dissemination underwent local RT only after STR. 7 Despite having a worse initial prognosis, the mean PFS for the 2 patients who underwent CSI was 83.5 months, while those who underwent local-only RT had a mean PFS of 53 months.…”
Section: Literature Review/discussionmentioning
confidence: 99%