Infectious Disease Clinics of North America volume 25, issue 4, P733-754 2011 DOI: 10.1016/j.idc.2011.07.003 View full text
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Praveen K. Mullangi, Lokesh Shahani, Janak Koirala

Abstract: Biologic response modifiers (BRMs) interact with the host immune system and modify the immune response. BRMs can be therapeutically used to restore, augment, or dampen the host immune response. Although they have been used for decades, their clinical applications have been expanded in the past decade for diagnosis and treatment of many diseases including cancers, immunologic disorders, and infections. This article discusses endogenous biological response modifiers (ie, naturally occurring immunomodulators as a…

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