1997
DOI: 10.1001/archderm.133.4.481
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Role of delayed cellular hypersensitivity and adhesion molecules in amoxicillin-induced morbilliform rashes

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Cited by 21 publications
(8 citation statements)
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“…From our results (1, 2, 5, 6) and those obtained from the literature, we consider that patch tests are of value in determining the responsible drug in generalized eczema, systemic contact dermatitis, baboon syndrome, maculopapular rash (1,2,5,6,24), AGEP (25), lichenoid rash and fixed drug eruption (11), and that photopatch tests may be useful in studying drug photosensitivity (10,26). On the other hand, they are of less value in investigating urticaria (1), Stevens-Johnson or Lyell's syndrome (25), pruritus or vasculitis (2).…”
Section: Commentmentioning
confidence: 61%
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“…From our results (1, 2, 5, 6) and those obtained from the literature, we consider that patch tests are of value in determining the responsible drug in generalized eczema, systemic contact dermatitis, baboon syndrome, maculopapular rash (1,2,5,6,24), AGEP (25), lichenoid rash and fixed drug eruption (11), and that photopatch tests may be useful in studying drug photosensitivity (10,26). On the other hand, they are of less value in investigating urticaria (1), Stevens-Johnson or Lyell's syndrome (25), pruritus or vasculitis (2).…”
Section: Commentmentioning
confidence: 61%
“…The most frequent reports of positive drug patch tests are related to the following drugs: betalactam antibiotics, especially amoxicillin (1,2,4,6,18,(24)(25)(26)(27)(28)(29)(30), cotrimoxazole (15), corticosteroids (1,31,32), heparin derivatives (1,(33)(34)(35)(36), pristinamycin (1,36), carbamazepine (1,2,20,(37)(38)(39)(40)(41)(42)(43)(44), diltiazem (1,45,46), diazepam (47), hydroxyzine (1,48), pseudoephedrine (1,21,22) and tetrazepam (1,16,(49)(50)(51).…”
Section: Commentmentioning
confidence: 99%
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“…In some cases of maculopapular exanthems, tested skin has been biopsied and found to present histological features similar to those of the original lesion with cell infiltrates like those in delayed hypersensitivity skin reactions of the tuberculin type (9,23,29,33,43), while in others, challenges with suspect b-lactams have confirmed à In addition, T-cell help in Ig-production/switch by some cytokines (e.g. IL-4, IL-5, IFN-c).…”
Section: Skin Testsmentioning
confidence: 99%