Role of CECT in Acute Pancreatitis and Correlation of MCTSI with Clinical Outcome

Abstract

Acute pancreatitis is one of the major complex abdominal pathology causing significant morbidity and mortality. CT imaging plays an important role in the diagnosis and staging of acute pancreatitis. The purpose of this study is to evaluate the role of CECT in characterization of acute pancreatitis and to assess the clinical outcome based on Modified CT severity index. Material and Methods: The study was done in a span of 1 year (January 2018 to December 2018) on all clinically and biochemically suspected cases of acute pancreatitis (study sample = 48). All these patients were subjected to CECT and scoring was based on Modified CT severity index (MCTSI). Results: The most commonly affected age group in this study was 41-50 years (58.33%) with a male predominance (62.5%). Cholelithiasis (43.75%) was observed to be the most common etiology followed by alcoholism (37.5%). The most common extrapancreatic complication was found to be pleural effusion (47.91%) followed by ascites (33.33%). Under MCTSI, patients were grades as mild, as moderate and as severe. The prognostic outcome (depending on parameters such as length of hospital stay need for intervention, presence of infection and solid organ failure) was significantly affected with increase in grade of acute pancreatitis. Conclusion: In conclusion, CECT plays a better role in identification and characterization of acute pancreatitis; and MCTSI is a better predictor of overall prognosis and clinical outcome.

A Study to Assess a correlation between serum amylase, lipase and Radiological imaging in patients with Acute Pancreatitis in a Tertiary care Hospital

“…Conirmation of Acute Pancreatitis can be done if the patient has Acute Abdominal pain, Elevated Serum Amylase and Lipase or CECT show characteristic indings (Bader and Azeem, 2018). Since CECT is costlier and more time consuming it should be performed in a case where the patient doesn't respond to therapy despite 48-72 hours of treatment (Gonapati et al, 2019). If there is no known history of Gall Bladder pathology or chronic alcoholism, then dyslipidemia and pancreatic tumour need to be ruled out as possible aetiology.…”

Comparison of the Accuracy of Modified CT Severity Index Score and Neutrophil-to-Lymphocyte Ratio in Assessing the Severity of Acute Pancreatitis

“…Multiple studies have compared other scoring systems for the diagnosis and prognosis of acute pancreatitis utilizing clinical and radiological scores [10][11][12]. The presenting symptoms of pancreatitis include sudden-onset severe abdominal pain, nausea, and vomiting, with the most common causes being gallstones and alcohol abuse [13][14][15]. In this study, we included all acute pancreatitis cases irrespective of the cause and compared MCTSI and NLR considering the revised Atlanta classification as the gold standard.…”