Role of Calcium in Bone Health During Childhood

Wosje, Karen S.; Specker, Bonny

doi:10.1111/j.1753-4887.2000.tb01879.x

Cited by 94 publications

(47 citation statements)

References 50 publications

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“…Fracture prevention is one of the key goals of osteoporosis therapy in postmenopausal women, with targets to inhibit bone loss processes, maintain proper bone strength, and minimise or eliminate the factors contributing to slips or falls (3) . The relationship between Ca intake and bone mineral density (BMD) is a widely analysed issue; higher Ca intake is associated with increased bone density in children (4) , as well as higher bone mass (5) , reduced risk of osteoporosis (6) and lower fracture risks (7) in adults and the elderly. The above-mentioned association is very complex and some authors emphasise the role of other factors, such as environmental factors for example, while doubting any strong correlation with Ca (8,9) .…”

mentioning

confidence: 99%

Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence – a population-based study in women over 55 years of age

Włodarek

Głąbska

Kołota

et al. 2012

Public Health Nutr.

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Objective: The incidence of osteoporosis increases with age and is most frequently observed in postmenopausal women. The objective of the present populationbased cohort study was to assess the influence of Ca intake from dairy sources on hip bone mineral density and hip fracture incidence in a group of Polish women over 55 years of age. Design: The main outcome measures included: bone mineral density, the number of previous fractures and the reported Ca intake from dairy sources, assessed by a diet questionnaire. Setting: The RAC-OST-POL Study was conducted in the District of Raciborz in the south of Poland. Subjects: The study was carried out in a group of 625 women, randomly recruited from the general population of women aged .55 years. Results: Median Ca intake from dairy products was lower in the group of women with femoral neck T-score #-2?5 than in the group with T-score .-2?5 (275 v. 383 mg/d; P 5 0?0019). For total hip score, the difference was close to borderline significance (P 5 0?0698). Median Ca intake from dairy products was lower in the group of women with previous fractures than in those without fracture history (336 v. 395 mg/d; P 5 0?0254). The main dairy source of Ca in the analysed group included milk drinks, rennet cheese and milk. Conclusions: Higher dairy Ca intake is recommended, since a number of the women analysed were unable to satisfy their Ca requirement exclusively from their diet.

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confidence: 99%

Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence – a population-based study in women over 55 years of age

Włodarek

Głąbska

Kołota

et al. 2012

Public Health Nutr.

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“…Calcium is often described as a threshold nutrient: skeletal mass increases with increasing calcium until intake reaches the level at which increasing gains are constant. The definition of the calcium threshold for children of varying ages remains in dispute (Wosje and Specker 2000). Phorphorous is another essential Jones and Dwyer (2000) did note a positive effect of winter solar exposure on the bone density of 8 year old Tasmanian children.…”

Section: Diet and Environment: Their Role In Bone Mineral Density Dietmentioning

confidence: 99%

Bone Mineral Density in Children From Anthropological and Clinical Sciences: A Review

Manifold¹

2014

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Bone mineral density (BMD) is a frequent topic of discussion in the clinical literature in relation to the bone health of both adults and children. However, in archaeological and/ or anthropological studies the role of BMD is often cited as a possible factor in the poor skeletal preservation which can lead to an under-representation of juvenile skeletal remains. During skeletal development and growth throughout childhood and adolescence changes take place in both the size and shape of bones and these changes also result in the increasing of mineral content. BMD can be affected by many factors, which include, age, genetics, sexual maturation, amount of physical activity and dietary calcium. This paper aims to review the clinical and anthropological literature on BMD and discuss the numerous methods of measurement and how the availability of certain methods such as Dual-energy x-ray absorptiometry (DEXA) and quantitative computed tomography (QCT) can influence the study of bone density in archaeological skeletal collections and also the future potential for forensic anthropological studies.

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“…9 A review of controlled trials documented an increase in the BMC of adolescents who took calcium supplements. 69 However, constipation secondary to neuropathic bowel is a frequent problem in patients with SB, and supplementation with calcium may exacerbate it. This side effect should be considered, and treatment of constipation in MMC children should be given when appropriate.…”

Section: Prevention and Non-pharmacological And Pharmacological Treatmentioning

confidence: 99%

Osteoporosis in paediatric patients with spina bifida

Marreiros

Loff

Calado

2012

The Journal of Spinal Cord Medicine

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The prevalence and morbidity associated with osteoporosis and fractures in patients with spina bifida (SB) highlight the importance of osteoporosis prevention and treatment in early childhood; however, the issue has received little attention. The method for the selection of appropriate patients for drug treatment has not been clarified. Objective: To review the literature concerning fracture risks and low bone density in paediatric patients with SB. We looked for studies describing state-of-the-art treatments and for prevention of secondary osteoporosis. Methods: Articles were identified through a search in the electronic database (PUBMED) supplemented with reviews of the reference lists of selected papers. The main outcome measures were incidence of fractures and risk factors for fracture, an association between bone mineral density (BMD) and occurrence of fracture, risk factors of low BMD, and effects of pharmacological and non-pharmacological treatments on BMD and on the incidence of fractures. We considered as a secondary outcome the occurrence of fractures in relation to the mechanism of injury. Results: Results indicated that patients with SB are at increased risk for fractures and low BMD. Risk factors that may predispose patients to fractures include higher levels of neurological involvement, non-ambulatory status, physical inactivity, hypercalciuria, higher body fat levels, contractures, and a previous spontaneous fracture. Limitations were observed in the number and quality of studies concerning osteoporosis prevention and treatment in paediatric patients with SB. The safety and efficiency of drugs to treat osteoporosis in adults have not been evaluated satisfactorily in children with SB.

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Role of Calcium in Bone Health During Childhood

Cited by 94 publications

References 50 publications

Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence – a population-based study in women over 55 years of age

Calcium intake and osteoporosis: the influence of calcium intake from dairy products on hip bone mineral density and fracture incidence – a population-based study in women over 55 years of age

Bone Mineral Density in Children From Anthropological and Clinical Sciences: A Review

Osteoporosis in paediatric patients with spina bifida

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