Roentgen Ray Therapy of Mycosis Fungoides

LEVIN, OSCAR L.

doi:10.1001/archderm.1945.01510230017003

Cited by 12 publications

(2 citation statements)

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“…The early approach to the management of MF using radiation was entirely palliative, largely because the ability to treat large skin surfaces safely was nonexistent. Individual lesions were treated with low doses of soft X‐rays (60–100 kV; half‐value layer = 1–1.5 mm Al) given at a rate of 0.75–1 Gy weekly, with total doses of 6–8 Gy (7). Although disease within the treated field was often controlled for a long period of time, patients inevitably returned on many occasions for the treatment of new lesions (8).…”

Section: Introductionmentioning

confidence: 99%

Mycosis fungoides: radiation therapy

Hoppe

2003

Dermatol Ther

101

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Radiation therapy is the most effective single agent for the treatment of mycosis fungoides. There are well‐defined dose–response relationships for achieving a complete response as well as the durability of this response. Techniques of electron beam therapy have been developed that permit treatment of the entire skin. Total‐skin electron beam therapy is an important form of management, especially for patients who have thick generalized plaque or tumorous disease. Radiation therapy may also be used selectively for treatment of extracutaneous disease.

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Section: Introductionmentioning

confidence: 99%

Mycosis fungoides: radiation therapy

Hoppe

2003

Dermatol Ther

101

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“…Radiation therapy-X-ray irradiation has been demonstrated to be palliative in CTCL. 48 The dose is fractionated: 75 rad to 500 rad to a total dose of 800 rad to 1500 rad. 5 A recent report focused on the combination of TSEB with whole body x-ray irradiation in 12 patients, 6 of whom had stage IIA CTCL; 3, stage III; and 3, stage IVA.49 Total doses were 150 rad irradiation and 3600 rad TSEB.…”

Section: Retinoidsmentioning

confidence: 99%

Treatment of cutaneous T-cell lymphoma: An update

Young¹

1993

Journal of Osteopathic Medicine

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Cutaneous T-cell lymphoma is a malignancy of T cells that have an affinity for the skin. Prognosis and treatment depend on accurate staging using the TNM system. Treatment for stage I disease, which includes oral methoxsalen plus ultraviolet radiation (with or without retinoids), nitrogen mustard, total skin electron beam, and photopheresis, is generally helpful. Therapy for stage II, III, or IV disease is not as successful. Extracorporeal photopheresis is an exciting new treatment that perhaps offers help for certain cases of advanced disease. Despite current modes of treatment, cutaneous T-cell lymphoma frequently results in death.

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