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Cited by 284 publications
(214 citation statements)
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“…Such variations have also been noted for RMSF (13). In the United States, the disease is in the midst of its third emergence since 1920, after peaking from 1939 to 1949, and again from 1974 to 1984 (13,14) (Figure 3).…”
Section: New Information About Epidemiologic Featuressupporting
confidence: 53%
“…Such variations have also been noted for RMSF (13). In the United States, the disease is in the midst of its third emergence since 1920, after peaking from 1939 to 1949, and again from 1974 to 1984 (13,14) (Figure 3).…”
Section: New Information About Epidemiologic Featuressupporting
confidence: 53%
“…1,2 Rocky Mountain spotted fever has long been considered one of the most severe tick-borne rickettsial infections, with preantibiotic case-fatality rates reported as high as 65-80% in some case series [1][2][3][4] ;contemporary estimates from 1981 to 1998 placed modern case-fatality rates at around 3% of reported cases. 5,6 The disease causes fever, headache, abdominal pain, and rash in a majority of patients, and may also lead to complications such as encephalitis, acute respiratory distress syndrome, and coagulopathies.…”
Section: Introductionmentioning
confidence: 99%
“…5,6 The disease causes fever, headache, abdominal pain, and rash in a majority of patients, and may also lead to complications such as encephalitis, acute respiratory distress syndrome, and coagulopathies. 1,2 Although most antibiotics are characteristically ineffective against R. rickettsii , tetracycylines offer excellent clinical results. However, a delay in administration of doxycycline, the recommended drug of choice, has been shown to increase the likelihood of fatal outcome.…”
Section: Introductionmentioning
confidence: 99%
“…Data herein reported follow a pattern observed in other regions of Brazil and alert to the fact that alternative measures of control should be implemented in this area studied. The Rhipicephalus (Boophilus) microplus (Canestrini, 1888) is the most important tick species which affect bovines in tropical areas, causing economical losses and transmitting pathogens (Dantas-Torres, 2007). Its control is based on the use of chemical compounds, being the arsenicals the first substance used, followed by organochlorids and organophosphorids (Graf et al, 2004).…”
Section: Introductionmentioning
confidence: 99%