Robust transmission regression models for linkage and association

Development of a RAPD marker‐based classification criterion for quality semen production in Holstein crossbred bulls

“…Schaid and Rowland (2000) adopted a regression model for accounting linkage and linkage disequilibria. Comparable regression statistics were also used by Knott et al.…”

Development of a RAPD marker‐based classification criterion for quality semen production in Holstein crossbred bulls

“…Schaid and Rowland (2000) adopted a regression model for accounting linkage and linkage disequilibria. Comparable regression statistics were also used by Knott et al.…”

Association of Megalin Genetic Polymorphisms with Prostate Cancer Risk and Prognosis

“…Using immunohistochemical assays, we have determined that neoplastic prostate epithelium expresses greater levels of megalin protein than adjacent benign epithelium. 10 We hypothesize that polymorphisms in the megalin gene that result in altered transport activity may influence the outcome of the disease. Our preliminary results suggest that genetic variants within the megalin gene may alter both risk of prostate cancerspecific death and disease recurrence/progression.…”

Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF–LTA) and breast cancer risk

“…A global score statistic was used to evaluate the overall diVerence in haplotype frequencies between cases and controls (Schaid et al 2002). Haplotypes were reconstructed, and haplotype frequencies and ORs (95% CIs), adjusted for matching factors, were estimated simultaneously using HaploStats (version 1.2.1; http://www.broad.mit.edu/mpg/haploview/download.php) (Schaid and Rowland 2000;Schaid et al 2002). Pairwise linkage disequilibrium (LD) was measured by r 2 and DЈ (Zondervan and Cardon 2004) in Haploview (http://www.broad.mit.edu/mpg/haploview/ index.php).…”

Development of a RAPD marker‐based classification criterion for quality semen production in Holstein crossbred bulls

“…Schaid and Rowland (2000) adopted a regression model for accounting linkage and linkage disequilibria. Comparable regression statistics were also used by Knott et al.…”

Association of Megalin Genetic Polymorphisms with Prostate Cancer Risk and Prognosis

“…Using immunohistochemical assays, we have determined that neoplastic prostate epithelium expresses greater levels of megalin protein than adjacent benign epithelium. 10 We hypothesize that polymorphisms in the megalin gene that result in altered transport activity may influence the outcome of the disease. Our preliminary results suggest that genetic variants within the megalin gene may alter both risk of prostate cancerspecific death and disease recurrence/progression.…”

Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF–LTA) and breast cancer risk

“…A global score statistic was used to evaluate the overall diVerence in haplotype frequencies between cases and controls (Schaid et al 2002). Haplotypes were reconstructed, and haplotype frequencies and ORs (95% CIs), adjusted for matching factors, were estimated simultaneously using HaploStats (version 1.2.1; http://www.broad.mit.edu/mpg/haploview/download.php) (Schaid and Rowland 2000;Schaid et al 2002). Pairwise linkage disequilibrium (LD) was measured by r 2 and DЈ (Zondervan and Cardon 2004) in Haploview (http://www.broad.mit.edu/mpg/haploview/ index.php).…”

Development of a RAPD marker‐based classification criterion for quality semen production in Holstein crossbred bulls

“…Schaid and Rowland (2000) adopted a regression model for accounting linkage and linkage disequilibria. Comparable regression statistics were also used by Knott et al.…”

Association of Megalin Genetic Polymorphisms with Prostate Cancer Risk and Prognosis

“…Using immunohistochemical assays, we have determined that neoplastic prostate epithelium expresses greater levels of megalin protein than adjacent benign epithelium. 10 We hypothesize that polymorphisms in the megalin gene that result in altered transport activity may influence the outcome of the disease. Our preliminary results suggest that genetic variants within the megalin gene may alter both risk of prostate cancerspecific death and disease recurrence/progression.…”

Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF–LTA) and breast cancer risk

“…A global score statistic was used to evaluate the overall diVerence in haplotype frequencies between cases and controls (Schaid et al 2002). Haplotypes were reconstructed, and haplotype frequencies and ORs (95% CIs), adjusted for matching factors, were estimated simultaneously using HaploStats (version 1.2.1; http://www.broad.mit.edu/mpg/haploview/download.php) (Schaid and Rowland 2000;Schaid et al 2002). Pairwise linkage disequilibrium (LD) was measured by r 2 and DЈ (Zondervan and Cardon 2004) in Haploview (http://www.broad.mit.edu/mpg/haploview/ index.php).…”