Robocasting of 45S5 bioactive glass scaffolds for bone tissue engineering

Eqtesadi, Siamak; Motealleh, Azadeh; Miranda, Pedro; Pajares, Antonia; Lemos, A.F.; Ferreira, J.M.F.

doi:10.1016/j.jeurceramsoc.2013.08.003

Cited by 142 publications

(101 citation statements)

References 46 publications

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“…They include filters, laboratory equipment, catalysts, and catalyst carriers (Robocasting Enterprises LLC). Extrusion freeformed parts may find usage as solid ceramic prototypes, [137] photonic bandgap structures, [119,[167][168][169] piezoactuators, [145] microbatteries, [170] graded structures, [160] biomaterials, [125,144,147,154,155,164,[171][172][173][174][175][176][177][178][179][180][181][182] as well as military and aerospace applications, such as radomes and missile propulsion nozzles. [160] …”

Section: Present and Future Applicationsmentioning

confidence: 99%

Additive Manufacturing of Ceramic‐Based Materials

et al. 2014

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This paper offers a review of present achievements in the field of processing of ceramic-based materials with complex geometry using the main additive manufacturing (AM) technologies. In AM, the geometrical design of a desired ceramic-based component is combined with the materials design. In this way, the fabrication times and the product costs of ceramic-based parts with required properties can be substantially reduced. However, dimensional accuracy and surface finish still remain crucial features in today's AM due to the layer-by-layer formation of the parts. In spite of the fact that significant progress has been made in the development of feedstock materials, the most difficult limitations for AM technologies are the restrictions set by material selection for each AM method and aspects considering the inner architectural design of the manufactured parts. Hence, any future progress in the field of AM should be based on the improvement of the existing technologies or, alternatively, the development of new approaches with an emphasis on parts allowing the near-net formation of ceramic structures, while optimizing the design of new materials and of the part architecture.

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Section: Present and Future Applicationsmentioning

confidence: 99%

Additive Manufacturing of Ceramic‐Based Materials

et al. 2014

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“…In the macro structure (Fig. 5), it is able to see spongy bone physical similarity, with large enough pores to contain biological structure, where the larger pores are about 500 micrometers, while there is a population of smaller pores with different diameters [25,26]. …”

Section: Scaffold Preparationmentioning

confidence: 99%

45S5 Bioglass porous scaffolds: structure, composition and bioactivity characterization

Abad-Javier¹,

Cajero-Juárez²,

García³

2016

Epitoanyag - JSBCM

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Advanced ceramics development is a promising area in regenerative medicine; although there are different biomaterials with features that make them viable enough, their improvement and optimization is required to produce biomaterials easier to bio assimilate and promote a faster tissue recovery. At this work a nanostructured bioglass based biomimetic scaffold is developed, beginning with the sol-gel synthesis parameters establishment coupled with a spray drying stage. through X-ray diffraction the crystal na 6 ca 3 si 6 o 18 phase was characterized, this phase is common to find in almost every 45s5 bioglass different synthesis processes, also a standard of mammalian hydroxyapatite was prepared to be used as a comparative control in determining the bioglass scaffold bioactivity. three-dimensional structure was characterized by optical and scanning electron microscopy, coupled to a semi-quantitative technique (eDs) to determine the composition of the synthesized biomaterial. subsequently, simulated body fluid (sBF) was used as an in vitro system, whose composition emulates the ionic blood concentration to evaluate the scaffold bioactivity.

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“…In contrast, the compressive strength values of the scaffold fabricated from 70-Di-10FA-20TCP ( Figure 4b) were significantly higher in comparison to those reported for cancellous bone (212 MPa) [36][37][38]. …”

Section: Alkali-free Bioactive Glass Compositionsmentioning

confidence: 83%

“…Other interesting features of these bioactive glass compositions are the easiness of dispersing the glass powder frits in aqueous suspensions and scaffold fabrication by additive manufacturing techniques [36]. The pH values of the suspensions are lower in comparison to those of 45S5 Bioglass® and the particle size of powder frits can be more conveniently reduced and expose a larger surface area to the dispersion liquid without undergoing a so extensive dissolution [37,38]. Still more important from the overall processing point of view is the excellent sintering ability, achieving full densification before the onset of crystallization, resulting in strong mechanical properties [25][26][27][28][31][32][33].…”

Section: Alkali-free Bioactive Glass Compositionsmentioning

confidence: 99%

“…Figure 4 compares porous scaffolds fabricated by robo casting, an extrusion based additive manufacturing technique that enables designing not only the external form and dimensions, but also tailoring the internal structure. The starting materials were 45S5 Bioglass® (Figure 4a) [37,38], and our alkali-free bioactive glass 70-Di-10FA-20TCP (Figure 4b) [36].…”

Section: Alkali-free Bioactive Glass Compositionsmentioning

confidence: 99%

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