Risperidone alone or in combination for acute mania

Medications for Adolescents and Young Adults With Autism Spectrum Disorders: A Systematic Review

“…13 Similarly, Cochrane reviews found substantial evidence for weight gain in adults with schizophrenia or bipolar disorder treated with risperidone. 15,16 When the broader evidence base is considered, the consistency of these findings supports an association of weight gain with risperidone in adults with ASD, just as is true in children with ASD and adults with other disorders. This approach to assessing the evidence for adverse events is outside of the scope of this review, but similar conclusions could be drawn with respect to sedation and extrapyramidal symptoms with risperidone or haloperidol.…”

Medications for Adolescents and Young Adults With Autism Spectrum Disorders: A Systematic Review

“…13 Similarly, Cochrane reviews found substantial evidence for weight gain in adults with schizophrenia or bipolar disorder treated with risperidone. 15,16 When the broader evidence base is considered, the consistency of these findings supports an association of weight gain with risperidone in adults with ASD, just as is true in children with ASD and adults with other disorders. This approach to assessing the evidence for adverse events is outside of the scope of this review, but similar conclusions could be drawn with respect to sedation and extrapyramidal symptoms with risperidone or haloperidol.…”

Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry

“…This fact might have led to the inclusion of a disproportional percentage of patients refractory to lithium and also of patients suffering from milder symptomatology in most recent studies [91]. Another problem with recent trials is the high drop-out rate that limits the generalizability of the results [411,412]. However, those high attrition rates might be at least partially attributable to higher ethical standards in modern studies.…”

Treatment of bipolar disorder: a systematic review of available data and clinical perspectives

“…This fact might have led to the inclusion of a disproportionate percentage of refractory to lithium patients and also of patients suffering from milder symptomatology in the most recent studies (Burgess et al, 2001). Another problem with recent trials is the high drop-out rate which limits the generalizability of the results (Rendell et al, 2003(Rendell et al, , 2006. Those high attrition rates, however, may be in part attributable to higher ethical standards in modern studies.…”

Medications for Adolescents and Young Adults With Autism Spectrum Disorders: A Systematic Review

“…13 Similarly, Cochrane reviews found substantial evidence for weight gain in adults with schizophrenia or bipolar disorder treated with risperidone. 15,16 When the broader evidence base is considered, the consistency of these findings supports an association of weight gain with risperidone in adults with ASD, just as is true in children with ASD and adults with other disorders. This approach to assessing the evidence for adverse events is outside of the scope of this review, but similar conclusions could be drawn with respect to sedation and extrapyramidal symptoms with risperidone or haloperidol.…”

Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry

“…This fact might have led to the inclusion of a disproportional percentage of patients refractory to lithium and also of patients suffering from milder symptomatology in most recent studies [91]. Another problem with recent trials is the high drop-out rate that limits the generalizability of the results [411,412]. However, those high attrition rates might be at least partially attributable to higher ethical standards in modern studies.…”

Treatment of bipolar disorder: a systematic review of available data and clinical perspectives

“…This fact might have led to the inclusion of a disproportionate percentage of refractory to lithium patients and also of patients suffering from milder symptomatology in the most recent studies (Burgess et al, 2001). Another problem with recent trials is the high drop-out rate which limits the generalizability of the results (Rendell et al, 2003(Rendell et al, , 2006. Those high attrition rates, however, may be in part attributable to higher ethical standards in modern studies.…”

Medications for Adolescents and Young Adults With Autism Spectrum Disorders: A Systematic Review

“…13 Similarly, Cochrane reviews found substantial evidence for weight gain in adults with schizophrenia or bipolar disorder treated with risperidone. 15,16 When the broader evidence base is considered, the consistency of these findings supports an association of weight gain with risperidone in adults with ASD, just as is true in children with ASD and adults with other disorders. This approach to assessing the evidence for adverse events is outside of the scope of this review, but similar conclusions could be drawn with respect to sedation and extrapyramidal symptoms with risperidone or haloperidol.…”

Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry

“…This fact might have led to the inclusion of a disproportional percentage of patients refractory to lithium and also of patients suffering from milder symptomatology in most recent studies [91]. Another problem with recent trials is the high drop-out rate that limits the generalizability of the results [411,412]. However, those high attrition rates might be at least partially attributable to higher ethical standards in modern studies.…”

Treatment of bipolar disorder: a systematic review of available data and clinical perspectives

“…This fact might have led to the inclusion of a disproportionate percentage of refractory to lithium patients and also of patients suffering from milder symptomatology in the most recent studies (Burgess et al, 2001). Another problem with recent trials is the high drop-out rate which limits the generalizability of the results (Rendell et al, 2003(Rendell et al, , 2006. Those high attrition rates, however, may be in part attributable to higher ethical standards in modern studies.…”