Risk of intervertebral disc joint puncture during lumbar puncture

Ertaş, Ahmet; Gediz, Tolga; Özdöl, Çağatay; Gürses, İlke Ali; Önder, Merve; Üzel, Mehmet; Aghayev, Kamran

doi:10.1016/j.clineuro.2020.106107

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…When conservative treatment methods, such as physical therapy, drug treatment, and epidural steroid injection fail, surgical intervention involving vertebral fusion is needed to reduce pain and other symptoms by limiting the movement of the diseased segment of the vertebral body [ 8 , 10 ]. However, the decreased activity of the vertebral body will accelerate the degenerative changes of the adjacent disc [ 9 , 41 ].…”

Section: Discussionmentioning

confidence: 99%

Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway

Wang

Yang

et al. 2023

Bioactive Materials

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Section: Discussionmentioning

confidence: 99%

Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway

Wang

Yang

et al. 2023

Bioactive Materials

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“…Despite being statistically insignificant, the declining efficacy ratio order from groups B to D suggests age-related dural compression [ 29 ]. Studies also report higher L4-5 iatrogenic disc injury risks [ 30 ], potentially causing degeneration and herniation [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Quantitative anatomical analysis of lumbar interspaces based on 3D CT imaging: optimized segment selection for lumbar puncture in different age groups

Zhuang,

Hu,

Dai

et al. 2024

Neuroradiology

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Background Optimal lumbar puncture segment selection remains controversial. This study aims to analyze anatomical differences among L3-4, L4-5, and L5-S1 segments across age groups and provide quantitative evidence for optimized selection. Methods 80 cases of CT images were collected with patients aged 10–80 years old. Threedimensional models containing L3-S1 vertebrae, dural sac, and nerve roots were reconstructed. Computer simulation determined the optimal puncture angles for the L3-4, L4-5, and L5-S1 segments. The effective dural sac area (ALDS), traversing nerve root area (ATNR), and area of the lumbar inter-laminar space (ALILS) were measured. Puncture efficacy ratio (ALDS/ALILS) and nerve injury risk ratio (ATNR/ALILS) were calculated. Cases were divided into four groups: A (10–20 years), B (21–40 years), C (41–60 years), and D (61–80 years). Statistical analysis was performed using SPSS. Results 1) ALDS was similar among segments; 2) ATNR was greatest at L5-S1; 3) ALILS was greatest at L5-S1; 4) Puncture efficacy ratio was highest at L3-4 and lowest at L5-S1; 5) Nerve injury risk was highest at L5-S1. In group D, L5-S1 ALDS was larger than L3-4 and L4-5. ALDS decreased after age 40. Age variations were minimal across parameters. Conclusion The comprehensive analysis demonstrated L3-4 as the optimal first-choice segment for ages 10–60 years, conferring maximal efficacy and safety. L5-S1 can serve as an alternative option for ages 61–80 years when upper interspaces narrow. This study provides quantitative imaging evidence supporting age-specific, optimized lumbar puncture segment selection.

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Can extracellular vesicles be considered as a potential frontier in the treatment of intervertebral disc disease?

Zhu,

Wang,

Suo

et al. 2023

Ageing Research Reviews

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Risk of intervertebral disc joint puncture during lumbar puncture

Cited by 5 publications

References 17 publications

Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway

Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway

Quantitative anatomical analysis of lumbar interspaces based on 3D CT imaging: optimized segment selection for lumbar puncture in different age groups

Can extracellular vesicles be considered as a potential frontier in the treatment of intervertebral disc disease?

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