Risk Factors of Extended-Spectrum &amp;beta;-Lactamase Producing Enterobacteriaceae Occurrence in Farms in Reunion, Madagascar and Mayotte Islands, 2016&amp;ndash;2017

Leclaire, Alexandre; Laval, Morgane; Miltgen, Guillaume; Jégo, Maël; Ramin, Susan; Jaubert, Julien; Belmonte, Olivier; Cardinale, Éric

doi:10.20944/preprints201801.0201.v1

Cited by 8 publications

(5 citation statements)

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“…South Africa (CTX-M), Madagascar (CTX-M-15), Nigeria (CTX-M and ND-ESBL), Tanzania (CTX-M-15) and Tunisia (CTX-M-15) also presented reports of E-ESBL in cattle. The reports were E. coli, Klebsiella sp, Salmonella sp, P. mirabilis, P. vulgaris, Providencia sp e Shigella spp (Gay et al, 2018;Iweriebor et al, 2015;Ogefere et al, 2017;Olowe et al, 2015;Saidani et al, 2018;Seni et al, 2016). In all countries the origin was faecal (except Tunisia, with mastitis also).…”

Section: Africamentioning

confidence: 99%

“…Escherichia coli Europe Germany Faecal (Wieler et al, 2011) Mastitis (Freitag et al, 2017;Michael et al, 2017) Diarrheic (Ewers et al, 2014) Sick (Michael et al, 2017) Infection (Brennan et al, 2016) Denmark Commensal (Kjeldsen et al, 2015) ND (Garcia-Fernandez et al, 2011;Jakobsen et al, 2015) Spain Mastitis (Briñas et al, 2005) Finland Faecal (P€ aiv€ arinta et al, 2016) France Faecal (Haenni et al, 2014;Hartmann et al, 2012;Madec et al, 2008;Meunier et al, 2006) Mastitis (Dahmen et al, 2013) Diarrheic (Hartmann et al, 2012) Sick (Madec et al, 2008;Valat et al, 2016) Infection (Meunier et al, 2006) Hungary Infection (Toth et al, 2013) Portugal Faecal (Ramos et al, 2013) Mayotte ND (Gay et al, 2018) Netherlands Faecal (Ceccarelli et al, 2019;Heuvelink et al, 2019;Hordijk et al, 2013a, b, c) United Kingdom…”

Section: Ctx-m-1mentioning

confidence: 99%

“…Faecal (Velasova et al, 2019) Infection (Hunter et al, 2010) ND (Stokes, 2014) Czech Republic Faecal (Dolejska et al, 2011b) Sick (Dolejska et al, 2013) R eunion ND (Gay et al, 2018) Slovakia Faecal (Kme t and Buj n akov a, 2018) Sweden Faecal (Duse et al, 2015) Switzerland Faecal (Endimiani et al, 2012;Geser et al, 2012a;Zurfluh et al, 2015) Turkey Faecal (AslantaŞ et al, 2017;Pehlivanoglu et al, 2016) North America Canada ND (Cormier et al, 2019) USA Faecal (Mir et al, 2016;Mollenkopf et al, 2012;Wittum et al, 2010) Asia China Mastitis (Ali et al, 2016(Ali et al, , 2017 South Korea Mastitis (Tark et al, 2017) Indonesia Faecal (Sudarwanto et al, 2016) Japan Mastitis (Ohnishi et al, 2013b) Klebsiella pneumoniaeEurope Italy Mastitis (Locatelli et al, 2010) Klebsiella ozaenae Italy Faecal (Stefani et al, 2014) Salmonella enterica Germany ND (Rodríguez et al, 2009) CTX-M-1/61 E. coli Europe Germany Faecal (Dahms et al, 2015) CTX-M-2 E. coli South America Brazil Faecal (Palmeira et al, 2018) Europe Germany Mastitis (Eisenberger et al, 2017;Freitag et al, 2017;Michael et al, 2017) Sick (Michael et al, 2017) Netherlands Faecal (Ceccarelli et al, 2019;Heuvelink et al, 2019) North America Canada Faecal (Cormier et al, 2016) Asia Japan Faecal (Shiraki et al, 2004) Diarrheic (Ohnishi et al, 2013a) Infection (Asai et al, 2011) K. pneumoniae Japan Mastitis (Ohnishi et...…”

Section: Ctx-m-1mentioning

confidence: 99%

“…Belgium, Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, Netherlands, Portugal, Slovakia, Spain, Sweden, Switzerland, Turkey and United Kingdom, presented at least one report of E-ESBL in cattle (AslantaŞ et al, 2017;Briñas et al, 2005;Dolejska et al, 2011b;Duse et al, 2015;Hordijk et al, 2013c;Hunter et al, 2010;Kjeldsen et al, 2015; Kme t and Buj n akov a, 2018; Michael et al, 2017;P€ aiv€ arinta et al, 2016;Pardon et al, 2017;Ramos et al, 2013;Stefani et al, 2014;Toth et al, 2013;Valat et al, 2016;Zurfluh et al, 2015). CTX-M-1 was described in 14 of the 16 countries with E-ESBL in cattle, CTX-M-15 present in 7, CTX-M-14 in 6 and CTX-M-3 and SHV-12 in 5 (AslantaŞ et al, 2017;Briñas et al, 2005;Dolejska et al, 2011b;Duse et al, 2015;Gay et al, 2018;Haenni et al, 2014;Hordijk et al, 2013b;Hordijk et al, 2013c;Hunter et al, 2010;Kjeldsen et al, 2015 (Dahms et al, 2015;Friese et al, 2013;Michael et al, 2017;Wieler et al, 2011;Wu et al, 2013). CTX-M-1, CTX-M-3, CTX-M-14, CTX-M-15 and SHV-12 have already been reported in E-ESBL in humans in Germany associated with infections (Gerhold et al, 2016;Mshana et al, 2009;Schmitt et al, 2007).…”

Section: Europementioning

confidence: 99%

“…In Africa, only 6 countries presented reports of E-ESBL in cattle. They were Egypt, Madagascar, Nigeria, South Africa, Tanzania and Tunisia (Braun et al, 2016;Gay et al, 2018;Iweriebor et al, 2015;Mkala and Azizi, 2017;Olowe et al, 2015;Saidani et al, 2018;Seni et al, 2016). There are not numerous nor descriptive reports on this continent.…”

Section: Africamentioning

confidence: 99%

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Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production – a threat around the world

Palmeira

Ferreira

2020

Heliyon

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Food producing animal is a global challenge in terms of antimicrobial resistance spread. Extended-spectrum betalactamase (ESBL)-producing Enterobacteriaceae are relevant opportunistic pathogens that may spread in many ecological niches of the One Health approach as human, animal and environment due to intestinal selection of antimicrobial resistant commensals in food production animals. Cattle production is a relevant ecological niche for selection of commensal bacteria with antimicrobial resistance from microbiota. Enterobacteriaceae show importance in terms of circulation of resistant-bacteria and antimicrobial resistance genes via food chain creating a resistance reservoir, setting up a threat for colonization of humans and consequent health risk. ESBL-producing Enterobacteriaceae are a threat in terms of human health responsible for life threatening outbreaks and silent enteric colonization of community populations namely the elder population. Food associated colonization is a risk difficult to handle and control. In a time of globalization of food trading, population intestinal colonization is a mirror of food production and in that sense this work aims to make a picture of ESBL-producing Enterobacteriaceae in animal production for food over the world in order to make some light in this reality of selection of resistant threats in food producing animal.

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Section: Africamentioning

confidence: 99%

Section: Ctx-m-1mentioning

confidence: 99%

Section: Ctx-m-1mentioning

confidence: 99%

Section: Europementioning

confidence: 99%

Section: Africamentioning

confidence: 99%

See 3 more Smart Citations

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production – a threat around the world

Palmeira

Ferreira

2020

Heliyon

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Effect of Intramuscularly Administered Oxytetracycline or Enrofloxacin on Vancomycin-Resistant Enterococci, Extended Spectrum Beta-Lactamase- and Carbapenemase-Producing Enterobacteriaceae in Pigs

González‐Fandos

Martínez‐Laorden

Abad-Fau

et al. 2022

Animals

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Nowadays, there is a great concern about the prevalence of multidrug resistant Enterococcus spp. and Enterobacteriaceae in food-producing animals. The aim of this work was to evaluate the effect of oxytetracycline or enrofloxacin treatment on vancomycin-resistant enterococci (VRE), extended spectrum β-lactamase (ESBL) and carbapenemase-producing Enterobacteriaceae in pigs. A total of 26 piglets were received and distributed in three groups. Group 1 was treated with enrofloxacin (N = 12), group 2 with oxytetracycline (N = 10) and group 3 did not receive any treatment (control group) (N = 4). A higher number of vancomycin-resistant E. faecium were recovered compared to E. faecalis. In the pigs treated with enrofloxacin, vancomycin resistant E. faecium was found in a higher percentage of animals than in the control group. ESBL-producing E. coli was not detected in rectal samples from control animals. However, it was detected in 17–20% of animals treated with oxytetracycline on days 6 to 17 and in 17–50% of the animals treated with enrofloxacin. Carbapenemase-producing E. coli was isolated in animals treated with oxytetracycline, but not in animals treated with enrofloxacin or in the control group. This study highlights that the use of oxytetracycline or enrofloxacin in food-producing animals could select ESBL and carbapenemase-producing E. coli. Further studies shall be needed to validate the results obtained, considering a more robust and extended experimental design.

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ESBL-Type and AmpC-Type Beta-Lactamases in Third Generation Cephalosporin-Resistant Enterobacterales Isolated from Animal Feces in Madagascar

Schotte,

Ehlers,

Nieter

et al. 2024

Animals

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Third generation cephalosporin-resistant (3GCR) Enterobacterales are known to be prevalent in Madagascar, with high colonization or infection rates in particular in Madagascan patients. Extended spectrum beta-lactamases (ESBLs) have been reported to be the predominant underlying resistance mechanism in human isolates. So far, little is known on antimicrobial resistance and its molecular determinants in Enterobacterales and other bacteria causing enteric colonization of Madagascan wild animals. To address this topic, swabs from 49 animal stool droppings were collected in the Madagascan Tsimanapesotsa National Park and assessed by cultural growth of bacterial microorganisms on elective media. In addition to 7 Acinetobacter spp., a total of 31 Enterobacterales growing on elective agar for Enterobacterales could be isolated and subjected to whole genome sequencing. Enterobacter spp. was the most frequently isolated genus, and AmpC-type beta-lactamases were the quantitatively dominating molecular resistance mechanism. In contrast, the blaCTX-M-15 gene, which has repeatedly been associated with 3GC-resistance in Madagascan Enterobacterales from humans, was detected in a single Escherichia coli isolate only. The identification of the fosfomycin-resistance gene fosA in a high proportion of isolates is concerning, as fosfomycin is increasingly used to treat infections caused by multidrug-resistant bacteria. In conclusion, the proof-of-principle assessment indicated a high colonization rate of resistant bacteria in stool droppings of Madagascan wild animals with a particular focus on 3GCR Enterobacterales. Future studies should confirm these preliminary results in a more systematic way and assess the molecular relationship of animal and human isolates to identify potential routes of transmission.

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Risk Factors of Extended-Spectrum β-Lactamase Producing Enterobacteriaceae Occurrence in Farms in Reunion, Madagascar and Mayotte Islands, 2016–2017

Cited by 8 publications

References 0 publications

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production – a threat around the world

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in cattle production – a threat around the world

Effect of Intramuscularly Administered Oxytetracycline or Enrofloxacin on Vancomycin-Resistant Enterococci, Extended Spectrum Beta-Lactamase- and Carbapenemase-Producing Enterobacteriaceae in Pigs

ESBL-Type and AmpC-Type Beta-Lactamases in Third Generation Cephalosporin-Resistant Enterobacterales Isolated from Animal Feces in Madagascar

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