Risk Factors for Various Causes of Failure in Initial Corneal Grafts

Abstract

Objective: To determine the risk factors for specific causes of initial corneal graft failure.Methods: This study analyzed corneal graft survival rates in a longitudinal noncomparative case series of 3992 consecutive penetrating keratoplasties performed at a single large referral center. Regrafts (n=352) were excluded from the analysis of risk factors for initial graft failure. Data were collected retrospectively from

Inadequate Results for Microkeratomeassisted Additive Stromal Keratoplasty for Management of Keratoconus

“…In one eye, a partially regressive corneal neovascularization due to an ulcer was noted; this can consequently increase the risk of rejection for a possible second planned graft. 23 The visual outcomes in our series were poor in comparison with those of the previously published study. 8 Several reasons may account for this.…”

Inadequate Results for Microkeratomeassisted Additive Stromal Keratoplasty for Management of Keratoconus

“…In one eye, a partially regressive corneal neovascularization due to an ulcer was noted; this can consequently increase the risk of rejection for a possible second planned graft. 23 The visual outcomes in our series were poor in comparison with those of the previously published study. 8 Several reasons may account for this.…”

The New Zealand National Eye Bank: Survival and Visual Outcome 1 Year After Penetrating Keratoplasty

“…Other published reports also cite glaucoma and infection as common reasons for PKP failure. 2,6,9,10 Overall visual outcome was also similar to that of other published reports, with 60% of recipients achieving a 1-year postoperative Donor factors (donor age, donor source, donor cause of death, DPI, ECD, and storage duration) were not significantly associated with decreased keratoplasty survival in this study. The results of this large New Zealand-based study tend to confirm trends that have previously been reported with respect to donor-related risk factors.…”

Histopathological Study of Delayed Regraft After Corneal Graft Failure

“…It is important to prevent failure of grafts because regrafts have a much poorer prognosis. [8][9][10][11][12] The mean age of the recipients at the age of the regraft (69.8 6 12.3 years) in our study was similar to another study from Canada. 13 Weisbrod et al also noticed that the average age of their patients undergoing regraft surgery was 5 years older than those undergoing surgery for the first time.…”

Inadequate Results for Microkeratomeassisted Additive Stromal Keratoplasty for Management of Keratoconus

“…In one eye, a partially regressive corneal neovascularization due to an ulcer was noted; this can consequently increase the risk of rejection for a possible second planned graft. 23 The visual outcomes in our series were poor in comparison with those of the previously published study. 8 Several reasons may account for this.…”

The New Zealand National Eye Bank: Survival and Visual Outcome 1 Year After Penetrating Keratoplasty

“…Other published reports also cite glaucoma and infection as common reasons for PKP failure. 2,6,9,10 Overall visual outcome was also similar to that of other published reports, with 60% of recipients achieving a 1-year postoperative Donor factors (donor age, donor source, donor cause of death, DPI, ECD, and storage duration) were not significantly associated with decreased keratoplasty survival in this study. The results of this large New Zealand-based study tend to confirm trends that have previously been reported with respect to donor-related risk factors.…”

Histopathological Study of Delayed Regraft After Corneal Graft Failure

“…It is important to prevent failure of grafts because regrafts have a much poorer prognosis. [8][9][10][11][12] The mean age of the recipients at the age of the regraft (69.8 6 12.3 years) in our study was similar to another study from Canada. 13 Weisbrod et al also noticed that the average age of their patients undergoing regraft surgery was 5 years older than those undergoing surgery for the first time.…”

Inadequate Results for Microkeratomeassisted Additive Stromal Keratoplasty for Management of Keratoconus

“…In one eye, a partially regressive corneal neovascularization due to an ulcer was noted; this can consequently increase the risk of rejection for a possible second planned graft. 23 The visual outcomes in our series were poor in comparison with those of the previously published study. 8 Several reasons may account for this.…”

The New Zealand National Eye Bank: Survival and Visual Outcome 1 Year After Penetrating Keratoplasty

“…Other published reports also cite glaucoma and infection as common reasons for PKP failure. 2,6,9,10 Overall visual outcome was also similar to that of other published reports, with 60% of recipients achieving a 1-year postoperative Donor factors (donor age, donor source, donor cause of death, DPI, ECD, and storage duration) were not significantly associated with decreased keratoplasty survival in this study. The results of this large New Zealand-based study tend to confirm trends that have previously been reported with respect to donor-related risk factors.…”

Histopathological Study of Delayed Regraft After Corneal Graft Failure

“…It is important to prevent failure of grafts because regrafts have a much poorer prognosis. [8][9][10][11][12] The mean age of the recipients at the age of the regraft (69.8 6 12.3 years) in our study was similar to another study from Canada. 13 Weisbrod et al also noticed that the average age of their patients undergoing regraft surgery was 5 years older than those undergoing surgery for the first time.…”