Risk Factors for Trauma-Induced Coagulopathy- and Transfusion-Associated Multiple Organ Failure in Severely Injured Trauma Patients

Abstract

BackgroundBoth trauma-induced coagulopathy (TIC) and transfusion strategies influence early outcome in hemorrhagic trauma patients. Their impact on late outcome is less well characterized. This study systematically reviews risk factors for TIC- and transfusion-associated multiple organ failure (MOF) in severely injured trauma patients.Materials and methodsA systematic search was conducted in PubMed and Embase. Studies published from 1986 to 2013 on adult trauma patients with an injury severity score ≥16, inves…