2020
DOI: 10.1097/shk.0000000000001589
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Abstract: Background: Severe heat stroke is a clinical syndrome caused by host stress dysfunction due to heat stress and subsequent life-threatening organ dysfunction. We aimed to explore the early risk factors affecting the 90-day prognosis of severe heat stroke patients. Methods: A case-control study was used to retrospectively analyze the clinical data of 117 severe heat stroke patients admitted to the intensive care unit of the General Hospital of Southern Theater Command from April 2014 to May 2019. The risk factor… Show more

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Cited by 13 publications
(8 citation statements)
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“…Studies have shown that abnormalities in platelet and coagulation function can re ect the severity of severe heat stroke. The application of anticoagulant therapy may help improve the survival rate of patients [25]. The current abnormalities in the blood coagulation mechanism caused by heat stroke may be related to the direct cytotoxic effect of thermal stimulation and the cellular in ammatory response induced by thermal stimulation, which leads to vascular endothelial damage and micro thrombosis [26][27].…”
Section: Discussionmentioning
confidence: 99%
“…Studies have shown that abnormalities in platelet and coagulation function can re ect the severity of severe heat stroke. The application of anticoagulant therapy may help improve the survival rate of patients [25]. The current abnormalities in the blood coagulation mechanism caused by heat stroke may be related to the direct cytotoxic effect of thermal stimulation and the cellular in ammatory response induced by thermal stimulation, which leads to vascular endothelial damage and micro thrombosis [26][27].…”
Section: Discussionmentioning
confidence: 99%
“…Internationally, the Sequential Organ Failure Assessment (SOFA) score is widely used to assess multiple organ dysfunction or failure as the main causes of death in critically ill patients 8 . Prior studies have suggested that the SOFA score is also useful for predicting mortality in patients with heatstroke 3 7 , 9 , 10 . However, those studies exhibited some weaknesses, including the use of populations comprising only exertional heatstroke, and single-center designs.…”
Section: Introductionmentioning
confidence: 99%
“…Some studies have also shown that RM caused by heatstroke may be an important factor in initiating sepsis (2)(3)(4)(5)(6) and will further cause the disturbance of blood coagulation, which can easily lead to the occurrence of DIC (7) and AKI (8,9). Research showed that the Sequential Organ Failure Assessment (SOFA) score was an independent risk factor affecting the survival of patients (10); therefore, treatments based on reducing the SOFA score may be pivotal for reducing the mortality of EHS complicated with AKI (11). However, so far there are few clinical studies on the clinical characteristics and prognosis of EHS complicated with RM, and there is no scoring system that can predict prognosis in patients with RM with EHS.…”
Section: Introductionmentioning
confidence: 99%