Risk Factors and the Clinical Course of Acute Kidney Injury in Patients with a Femoral Fracture

Yun, Yu-Seon; Yu, Jin; Kim, Jihee; Kwon, Ki Wook; Lee, Hong Seok; Lee, Yeong Bok; Bahk, Won Jong; Kim, Young Ok

doi:10.3904/kjm.2013.84.6.818

Cited by 2 publications

(3 citation statements)

References 23 publications

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“…Early diagnosis of AKI would be possible, and elderly patients with severe AKI did not undergo surgery. The reported incidence of AKI in elderly patients undergoing hip fracture surgery ranges from 15.3–24.4% according to the definition of AKI and varies with the considered population [ 2 , 3 , 6 , 8 , 10 , 30 ]. Elderly patients are particularly susceptible to developing AKI.…”

Section: Discussionmentioning

confidence: 99%

“…AKI following hip fracture has multi-factorial causes. Baseline renal function, age, comorbidities, dehydration, nephrotoxic drugs, and malnutrition are documented risk factors for AKI [ 2 , 3 , 8 , 13 , 17 , 21 , 31 ]. In our study, the baseline serum level of creatinine, use of ACE inhibitors or ARBs, RBC transfusion volume, and history of CAD were significantly associated with an increased risk of AKI, while the use of NSAIDs was not.…”

Section: Discussionmentioning

confidence: 99%

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Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery

et al. 2017

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BackgroundHip fracture is a common health problem in the elderly that is associated with increased mortality. Acute kidney injury (AKI) is a frequent complication in elderly patients undergoing surgery and is associated with the clinical outcome. We evaluated the incidence and risk factors of AKI in elderly patients undergoing hip fracture surgery and the impact of AKI on short- and long-term clinical outcomes.MethodsWe performed a retrospective cohort study of 450 elderly patients who underwent hip fracture surgery between January 2010 and December 2012. We defined AKI according to the Acute Kidney Injury Network (AKIN) criteria and investigated the effect of AKI on the duration of hospital stay and in-hospital and long-term mortality.ResultsOf the 450 patients, 95 (21.1%) developed AKI during hospitalization and 178 (39.6%) died, with a mean follow-up of 3.6 ± 1.0 years. The baseline serum creatinine level, use of angiotensin-converting enzyme inhibitors or angiotensin-II receptor antagonists, red blood cell transfusion volume, and history of coronary artery disease were independent risk factors for AKI. Patients with AKI during hospitalization had significantly longer hospital stays and higher in-hospital and long-term mortality than those without AKI. Multivariate analysis revealed that age, history of coronary artery disease, serum albumin level, and AKI were independent predictors of long-term mortality.ConclusionsAKI is a frequent complication in elderly patients undergoing hip fracture surgery and is independently associated with increased in-hospital and long-term mortality.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery

et al. 2017

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“…AKI development has been studied in patients undergoing hip fracture surgery with a reported prevalence ranging from 15.3% to 24.4% [17][18][19][20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Acute Kidney Injury in Hospitalised Medical Patients: Aetiology and Prognosis

Díaz-Peromingo

Beceiro-Abad

Freire-Romero

et al. 2018

AJMAH

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Background: Acute Kidney Injury (AKI) increases the length of hospitalisation and mortality. The study aims to assess the incidence, risk factors and outcome of AKI in hospitalised medical patients. Methods: AKI was measured in adult patients by using the serum creatinine criteria. Baseline data included age, sex, diagnosis during admission, pathological records, analytical data, use of nephrotoxic drugs, length of hospital stay, mortality at the hospital and during the follow-up, and the cause of death. Results: A total of 100 patients were included with a mean age of 75.6 years. Majority of male patients (n= 23; 56%) were showed AKI development. The most frequent associated diseases were hypertension, type 2 diabetes mellitus, and heart failure. Hospital stay was greater than 10 days in 52 patients. The patients who developed AKI were older, and had an increased prevalence of heart failure, hypertension, diarrhoea, anaemia, increased BUN, impaired GFR, and were most frequent under ARBs or diuretics. Mortality was higher in the AKI group during hospitalisation.

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Risk Factors and the Clinical Course of Acute Kidney Injury in Patients with a Femoral Fracture

Cited by 2 publications

References 23 publications

Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery

Acute kidney injury can predict in-hospital and long-term mortality in elderly patients undergoing hip fracture surgery

Acute Kidney Injury in Hospitalised Medical Patients: Aetiology and Prognosis

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