Right posterior cortical functions in a tumour patient series

Shallice, Tim; Mussoni, Alessandro; D'Agostino, Serena; Škrap, Miran

doi:10.1016/j.cortex.2010.04.005

Cited by 44 publications

(31 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3). This goes against the hypothesis that the removed regions were not implicated in visuospatial processing, and is consistent with the idea that no restricted cortical lesion is sufficient to produce attentional deficits (Bartolomeo, 2011;Shallice et al, 2010. The present findings would rather suggest that these patients had already recruited remotely connected regions to compensate for functional loss.…”

Section: 2supporting

confidence: 56%

“…In the remaining patients, tumour resection impaired lateralized target detection (accuracy and RTs) and visual exploration (see Shallice et al, 2010 for similar results, p1185). Deficits in detection and visual exploration occurred after resections in similar sites (see panel B in Fig.…”

Section: 2mentioning

confidence: 67%

“…Proportion of detected targets and Standard deviations on the left and right sides as a function of Session 1, 2 for Controls and of Session 1, 2, 3 for NP Patients (n ¼ 13) and P Patients (n ¼ 7; Patients: 1,8,12,13,14,16,17). 8 Note, however, that patients harbouring low grade glioma may sometimes present specific deficits which can be associated to brain localization (Shallice et al, 2010). Right parietal tumour patients in the Shallice et al study tend to have lower scores in visual search (star cancellation) than more frontal patients.…”

Section: Pre-operative Reorganization Of the Attention Networkmentioning

confidence: 95%

“…Even though a direct comparison between the findings by Shallice et al (2010) and ours is not immediate, because of our use of awake surgery and other methodological differences (such as the presence of patients with high-grade glioma in the Shallice et al study), our results are consistent with Shallice et al's proposal (Shallice et al 2010) that deficits stemming from brain tumours and their surgery can allow valid conclusions about function localizations (see Bartolomeo, 2011;Duffau, 2011). Anatomo-functional correlations with slowgrowing lesions are only valid when functional compensation mainly rests on local reorganization in peri-lesional areas.…”

Section: 2mentioning

confidence: 98%

“…Regardless of tumour localization within the right hemisphere, low grade glioma patients showed a deterioration in visual exploration (e.g., Star cancellation task) after operation, thus supporting the involvement of right-sided fronto-parietal networks in neglect (Bartolomeo, 2006;Bartolomeo et al, 2007;Bartolomeo et al, 2012). Nevertheless, the role of tumour localization on the type of deficits is challenged by the concurrent observation that patients harbouring low grade glioma in parieto-occipital regions tended to perform worse on the Star cancellation task than patients in the prefrontal group (independently of pre or post-surgery; Shallice, Mussoni, D'Agostino, & Skrap, 2010).…”

Section: Introductionmentioning

confidence: 93%

See 4 more Smart Citations

Functional reorganization of the attentional networks in low-grade glioma patients: A longitudinal study

Charras

Herbet

Deverdun

et al. 2015

Cortex

View full text Add to dashboard Cite

Section: 2supporting

confidence: 56%

Section: 2mentioning

confidence: 67%

Section: Pre-operative Reorganization Of the Attention Networkmentioning

confidence: 95%

Section: 2mentioning

confidence: 98%

Section: Introductionmentioning

confidence: 93%

See 3 more Smart Citations

Functional reorganization of the attentional networks in low-grade glioma patients: A longitudinal study

Charras

Herbet

Deverdun

et al. 2015

Cortex

View full text Add to dashboard Cite

Studying cognitive functions by means of direct electrical stimulation: a review

Papagno

2017

Neurol Sci

View full text Add to dashboard Cite

In recent years, neurosurgical patients have highly contributed to research in behavioural neurology. This development is in part due to the use of direct electrical stimulation during brain surgery. Indeed, during surgery for a tumour, involving both grey and white matter, it has become a common clinical practice to awaken patients with the aim of investigating the functional role of restricted brain areas. The surgeon can optimize the extent of resection and improve overall survival without causing permanent neurological deficits, owing to individual, specific mapping and preservation of eloquent structures. This type of mapping offers a unique opportunity to investigate the functional connectivity of the brain, permitting real-time anatomo-functional correlations, in awaken patients undergoing surgery. By gathering all cortical and axonal sites in which stimulation produces the same types of error, one can build up a picture of the network underlying the disrupted function. In this review, the main achievements concerning networks involved in some aspects of language, visuo-spatial cognition, calculation and emotion will be highlighted.

show abstract

Pre- and post-operative assessment of visuo-spatial functions in right hemisphere tumour patients: a pilot study

et al. 2012

View full text Add to dashboard Cite

Patients with neglect fail to report, respond to, or orient to stimuli presented on the opposite side of the brain lesion. Spatial neglect is a multi-componential syndrome and many of its symptoms and signs need specific testing to detect their different clinical manifestations. Given that neglect has a dramatic effect on the outcome of these patients, it is of paramount importance for accurate assessment all its manifestations. Thus, the purpose of this study is to assess visuo-spatial functions with a newly-built neuropsychological battery to determine the incidence of visuo-spatial disorders and spatial neglect in patients with right brain tumour. We tested 14 patients undergoing tumour resection, both pre-operatively and post-operatively. Pre-operatively, we found an incidence of 42.86% for visuo-spatial deficits and of 14.29% specifically for spatial neglect. This incidence increases post-operatively to 57.14% for visuo-spatial deficits and to 42.86% specifically for spatial neglect. The present study has important implications for a better knowledge of the spatial disorders in patients with right-brain tumour, thus providing a clearer picture on the everyday life problems faced by these patients, both within the family and in working contexts.

show abstract

Right posterior cortical functions in a tumour patient series

Cited by 44 publications

References 51 publications

Functional reorganization of the attentional networks in low-grade glioma patients: A longitudinal study

Functional reorganization of the attentional networks in low-grade glioma patients: A longitudinal study

Studying cognitive functions by means of direct electrical stimulation: a review

Pre- and post-operative assessment of visuo-spatial functions in right hemisphere tumour patients: a pilot study

Contact Info

Product

Resources

About