Rhythm of Sebum Excretion during the Menstrual Cycle

Piérard-Franchimont, C; Pierard, Gérald; Kligman, Albert M.

doi:10.1159/000247796

Cited by 35 publications

(17 citation statements)

References 4 publications

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“…Skin temperature and the balance between the sebum molecular components affect the viscosity and rheology of lipids at the skin surface [62,73]. This could explain in part chronobiological variations in SER and FER including seasonal fluctuations [74] as well as the influence of ovarian [75,76] and perhaps other cycles of unknown periodicity [7]. A circadian rhythm has been found [63,77] with sebum output being greatest in the mid morning and minimal during the late evening and early morning hours.…”

Section: Factors Affecting Sebum Excretionmentioning

confidence: 99%

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EEMCO Guidance for the in vivo Assessment of Skin Greasiness

Pierard

Piérard-Franchimont

Marks

et al. 2000

Skin Pharmacol Physiol

140

119

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Sebaceous gland activity has four distinct components which are sebum production (a secretion rate function), storage (a volume function), surface output (a delivery rate function) and stratum corneum permeation (an influx rate function). The oily appearance of skin results from an excess of sebum excretion and spreading over the body surface and its interaction with the skin surface. A multi-pronged approach is often useful to assess skin greasiness with precision. The clinical evaluation of skin greasiness and its shiny appearance should be further complemented by quantifying the large pores, follicular plugs and comedones. The sebum amount present at the skin surface can be measured non-invasively using one of several methods based on solvent extraction, cigarette paper pads, photometric assessment, bentonite clay and lipid-sensitive tapes. Quantitative parameters include the sebum casual level, the sebum excretion rate, the sebum replacement time, the instant sebum delivery, the follicular excretion rate, the density in sebum-enriched reservoirs and the sustainable rate of sebum excretion. A series of environmental and biological features influence the data. Hence rigorous methodological designs are mandatory to support claims. As a rule, accuracy of the methods is adversely affected by skin temperature, degree of hydration and surface roughness. An additional confounding factor is the inherent difficulty of collecting the surface lipids without a contribution from the follicular reservoir. A better understanding of factors that alter the sebum amount at the skin surface may well assist in the development of sebosuppressive agents to help the reduction of the skin greasiness and improve acne.

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Section: Factors Affecting Sebum Excretionmentioning

confidence: 99%

“…There is an inverse relationship between the fluid flux and the fourth power of the radius of the tube in which the fluid passes through. Hence, variations in corneocyte hydration at the lips of follicular openings, as may occur during the ovarian cycle or after occlusion, may influence sebum rheology [75,76,78,79].…”

Section: Factors Affecting Sebum Excretionmentioning

confidence: 99%

EEMCO Guidance for the in vivo Assessment of Skin Greasiness

Pierard

Piérard-Franchimont

Marks

et al. 2000

Skin Pharmacol Physiol

140

119

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“…Il existe aussi une autre périodicité importante de type circannuel à laquelle correspondent des manifestations saisonnières [6][7][8][9]. Bien d'autres biorythmes, tels que les rythmes cardiaque, respiratoire et ovarien, sont indépendants de la position de la Terre par rapport au Soleil [2,10,11].…”

Section: Introductionunclassified

Chronophysiologie circadienne du cuir chevelu

Piérard‐Franchimont

Henry

Loussouarn

et al. 2007

Pathologie Biologie

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RésuméLes rythmes biologiques sont nombreux et ils sont également variés selon leurs périodicités et amplitudes. Des variations au cours du jour, et en particulier des rythmes circadiens ont été rapportés au niveau de la peau du visage et des avant-bras. Cependant, peu d'information existe au niveau des biorythmes quotidiens du cuir chevelu. Le but de l'étude était d'explorer la chronophysiologie du cuir chevelu. Nous rapportons des rythmes diurnes chez huit hommes caucasiens. Ils sont révélés par la méthode des plexogrammes par intervalles de quatre heures sur une période de cinq jours. Des biorythmes statistiquement significatifs furent retrouvés pour la couleur de la peau, son hydratation, sa fonction barrière, son pH et l'excrétion de sébum. Le début de l'après-midi était le moment d'accroissement maximum de la rougeur, de l'hydratation, du pH et du débit sébacé. Il correspondait aussi à la diminution maximale de la fonction barrière cutanée. L'amplitude de certains de ces biorythmes était si faible que leur pertinence clinique reste incertaine, même si le caractère statistique est significatif. Compte tenu de leur synchronisme apparent, il est probable qu'un oscillateur central exerce une influence prépondérante. Cependant, rares sont les individus qui expriment des biorythmes pour tous les paramètres physiologiques considérés. La réactivité périphérique joue donc également un rôle important pour définir les bons et les mauvais répondeurs au biorythme potentiel de chaque paramètre individuel. © 2007 Elsevier Masson SAS. Tous droits réservés. AbstractBiological rhythms are numerous and vary according to periodicity and amplitude. Variations over the course of a day, particularly circadian rhythms have been reported in the skin of the face and forearms. However, little information is available about daily biorhythms of the scalp. The aim of the present study was to explore the chronophysiology of the scalp. We report a series of diurnal rhythms in 8 Caucasian men using the plexogram method at 4-h intervals over a 5-day period. Statistically significant biorhythms were found for the colour, hydration, barrier function and pH of the skin, and for the sebum excretion as well. The early afternoon was the time of maximum increase in redness, hydration, pH and sebum output, combined with decreased skin barrier function. The amplitude of some of these biorhythms was so discrete that their clinical relevance remained uncertain even when they appeared statistically significant. In view of the apparent synchronization between them, it is likely that a central oscillator exerts a major influence. However, only rare subjects exhibited biorhythms for all the considered physiological parameters. Hence, peripheral reactivity and/or environmental synchronizers also play an important role to define the good and bad respondors to the potential biorhythms of each individual parameter.

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“…The amount of sebum may be quantified by morphometry [4][5][6][7][8][9][10] or transmission pho tometry [111-Experience had taught us that sebum drop lets modify the 'white' color of Sebutape into the color of the skin itself. In this study, we wanted to explore the possibility of measuring these color modifications by reflectance colo rimetry at multiple intervals.…”

Section: Introductionmentioning

confidence: 99%

Kinetics of Sebum Excretion Evaluated by the Sebutape<sup>®</sup> – Chromameter<sup>®</sup> Technique

Pierard

Piérard-Franchimont

Kligman

1993

Skin Pharmacol Physiol

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We present a novel method for studying the changing characteristics of sebum excretion of facial skin over a 3-hour period. Sebum production can be quantified by analysis of the pore patterns formed on a sebum-sensitive tape (Sebutape^®). We applied the CIE principles of reflectance colorimetry by measuring L*, a* and b* of Sebutapes every 15 min during 3 h of sebum collection. This combined technique yielded valuable new informations on the kinetics of sebum excretion, allowing the distinction between the follicular reservoir effect and the sebum flow.

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Rhythm of Sebum Excretion during the Menstrual Cycle

Cited by 35 publications

References 4 publications

EEMCO Guidance for the in vivo Assessment of Skin Greasiness

EEMCO Guidance for the in vivo Assessment of Skin Greasiness

Chronophysiologie circadienne du cuir chevelu

Kinetics of Sebum Excretion Evaluated by the Sebutape<sup>®</sup> – Chromameter<sup>®</sup> Technique

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