Rhegmatogenous Retinal Detachment Following Cryotherapy in Retinopathy of Prematurity

Giant Retinal Tear With Retinal Detachment in Regressed Aggressive Posterior Retinopathy of Prematurity Treated by Laser

“…It is known that cryotherapy leads to more inflammation and increased pars plana and ciliary body pigmentation release compared to laser photocoagulation 8. Similar findings noted by Greven and Tasman7 may explain the early development of retinal detachment in cases treated with cryotherapy as opposed to laser photocoagulation 7. This also suggests that cases in which heavy laser burns are applied to extensive areas behave more like cases treated with cryotherapy.…”

Giant Retinal Tear With Retinal Detachment in Regressed Aggressive Posterior Retinopathy of Prematurity Treated by Laser

“…It is known that cryotherapy leads to more inflammation and increased pars plana and ciliary body pigmentation release compared to laser photocoagulation 8. Similar findings noted by Greven and Tasman7 may explain the early development of retinal detachment in cases treated with cryotherapy as opposed to laser photocoagulation 7. This also suggests that cases in which heavy laser burns are applied to extensive areas behave more like cases treated with cryotherapy.…”

Late Recurrence of Retinal Detachment

“…Ade quate retinopexy is necessary to maintain reattachment, and insufficient cryotherapy was probably involved in the 6 cases o f definite reopened peripheral tear. On the other hand, excessive cryotherapy may have contributed to the creation of new tears near the initially treated area (5 cases in this series), a possibility already mentioned by others [1,5,10].…”

Estrogen therapy to treat retinopathy in newborn mice

“…As reported in the International Classification of Retinopathy of Prematurity (3,4) and a multi-center clinical trial on retinopathy of prematurity (ROP) (5-9), current treatments for ROP mainly include cryotherapy and laser photocoagulation for threshold ROP, as well as sclera buckling and vitrectomy at a later stage. Although these procedures do significantly reduce the long-term adverse outcomes of ROP, such as blindness and retinal detachment, they may cause permanent damage to the retinal structure and are associated with life-long eye problems, including visual field defects and refractive error (10)(11)(12)(13). Researchers have, therefore, increasingly focused on preventing ROP progression by inhibiting angiogenesis based on the pathogenesis of ROP (14)(15)(16)(17)(18)(19)(20)(21)(22)(23).…”

Giant Retinal Tear With Retinal Detachment in Regressed Aggressive Posterior Retinopathy of Prematurity Treated by Laser

“…It is known that cryotherapy leads to more inflammation and increased pars plana and ciliary body pigmentation release compared to laser photocoagulation 8. Similar findings noted by Greven and Tasman7 may explain the early development of retinal detachment in cases treated with cryotherapy as opposed to laser photocoagulation 7. This also suggests that cases in which heavy laser burns are applied to extensive areas behave more like cases treated with cryotherapy.…”

Late Recurrence of Retinal Detachment

“…Ade quate retinopexy is necessary to maintain reattachment, and insufficient cryotherapy was probably involved in the 6 cases o f definite reopened peripheral tear. On the other hand, excessive cryotherapy may have contributed to the creation of new tears near the initially treated area (5 cases in this series), a possibility already mentioned by others [1,5,10].…”

Estrogen therapy to treat retinopathy in newborn mice

“…As reported in the International Classification of Retinopathy of Prematurity (3,4) and a multi-center clinical trial on retinopathy of prematurity (ROP) (5-9), current treatments for ROP mainly include cryotherapy and laser photocoagulation for threshold ROP, as well as sclera buckling and vitrectomy at a later stage. Although these procedures do significantly reduce the long-term adverse outcomes of ROP, such as blindness and retinal detachment, they may cause permanent damage to the retinal structure and are associated with life-long eye problems, including visual field defects and refractive error (10)(11)(12)(13). Researchers have, therefore, increasingly focused on preventing ROP progression by inhibiting angiogenesis based on the pathogenesis of ROP (14)(15)(16)(17)(18)(19)(20)(21)(22)(23).…”

Giant Retinal Tear With Retinal Detachment in Regressed Aggressive Posterior Retinopathy of Prematurity Treated by Laser

“…It is known that cryotherapy leads to more inflammation and increased pars plana and ciliary body pigmentation release compared to laser photocoagulation 8. Similar findings noted by Greven and Tasman7 may explain the early development of retinal detachment in cases treated with cryotherapy as opposed to laser photocoagulation 7. This also suggests that cases in which heavy laser burns are applied to extensive areas behave more like cases treated with cryotherapy.…”

Late Recurrence of Retinal Detachment

“…Ade quate retinopexy is necessary to maintain reattachment, and insufficient cryotherapy was probably involved in the 6 cases o f definite reopened peripheral tear. On the other hand, excessive cryotherapy may have contributed to the creation of new tears near the initially treated area (5 cases in this series), a possibility already mentioned by others [1,5,10].…”

Estrogen therapy to treat retinopathy in newborn mice

“…As reported in the International Classification of Retinopathy of Prematurity (3,4) and a multi-center clinical trial on retinopathy of prematurity (ROP) (5-9), current treatments for ROP mainly include cryotherapy and laser photocoagulation for threshold ROP, as well as sclera buckling and vitrectomy at a later stage. Although these procedures do significantly reduce the long-term adverse outcomes of ROP, such as blindness and retinal detachment, they may cause permanent damage to the retinal structure and are associated with life-long eye problems, including visual field defects and refractive error (10)(11)(12)(13). Researchers have, therefore, increasingly focused on preventing ROP progression by inhibiting angiogenesis based on the pathogenesis of ROP (14)(15)(16)(17)(18)(19)(20)(21)(22)(23).…”