Rezidivierende Ulzerationen bei Livedovaskulopathie

Becker, Annie; Stoffels-Weindorf, Maren; Schimming, Tobias; Dissemond, Joachim

doi:10.1055/s-0033-1343293

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…Its pathogenesis involves the focal non-inflammatory thrombosis of dermal veins and venulae in the subpapillary vascular plexus [39,40] that can usually be observed in histopathological examinations [41,42]. Other features include epidermal spongiosis or atrophy in the margin area, vessel wall thickening with endothelial proliferation, fibrinoid degeneration, fibrin deposits and fibrin thrombi in the lumen [38,39,[43][44][45][46]. Subintimal hyalinization and the absence of perivascular inflammation are characteristic, even though secondary inflammatory changes may be observed in later stages [38,42,44,47] (see Table 2, Figure 2).…”

Section: Livedoid Vasculopathymentioning

confidence: 99%

The Histopathology of Leg Ulcers

Hofmann,

Deinsberger,

Oszwald

et al. 2024

Dermatopathology

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Ulcerations of the lower extremities are a frequently encountered problem in clinical practice and are of significant interest in public health due to the high prevalence of underlying pathologies, including chronic venous disease, diabetes and peripheral arterial occlusive disease. However, leg ulcers can also present as signs and symptoms of various rare diseases and even as an adverse reaction to drugs. In such cases, correct diagnosis ultimately relies on histopathological examination. Apart from the macroscopic presentation, patient history and anatomic location, which are sometimes indicative, most ulcers have very distinct histopathological features. These features are found in different layers of the skin or even associated vessels. In this narrative review, we discuss and highlight the histopathological differences of several types of leg ulcers that can contribute to efficient and accurate diagnosis.

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Section: Livedoid Vasculopathymentioning

confidence: 99%

The Histopathology of Leg Ulcers

Hofmann,

Deinsberger,

Oszwald

et al. 2024

Dermatopathology

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Das verfärbte Bein

Füeßl

2018

CME

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Differenzialdiagnostische Fallstricke aus der Dermatochirurgie

John¹,

John²,

Friedling³

et al. 2018

Dtsch med Wochenschr

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Evaluation of skin diseases can be challenging for non-dermatologists. Even obvious well-characterized skin pathologies might be misleading and thus treatment can fail. Particularly the differentiation of surgical treated entities is important, for example the management of a wound healing disturbance profoundly differs from that of a pyoderma gangrenosum. This article outlines several easily mistaken pairs of dermatologic entities on one hand and surgical on the other. For example, a livedo vasculopathy can be confused with a leg ulcer, a nail melanoma with a simple hematoma and finally a hidradenitis suppurativa with an axillary abscess. Typical clinical signs and anamnestic data may often lead to the right diagnosis also assisted by the simple fact to “keep it in mind“.

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Rezidivierende Ulzerationen bei Livedovaskulopathie

Cited by 3 publications

References 10 publications

The Histopathology of Leg Ulcers

The Histopathology of Leg Ulcers

Das verfärbte Bein

Differenzialdiagnostische Fallstricke aus der Dermatochirurgie

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