Revisiting the supernumerary: the epidemiological and molecular basis of extra teeth

Fleming, Padhraig S.; Xavier, Guilherme M.; DiBiase, Andrew T.; Cobourne, Martyn T.

doi:10.1038/sj.bdj.2009.1177

Cited by 72 publications

(65 citation statements)

References 50 publications

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“…Supernumerary teeth are those present in addition to the normal complement within the dentition. They are generally classified according to morphology: supplemental supernumeraries have relatively normal size and shape, and resemble (usually adjacent) teeth within the dentition; rudimentary supernumeraries are small and abnormally shaped, being either conical or tuberculate in their primary morphology, while odontomes are hamartomatous malformations containing dental hard tissues of varying levels of organization74,75 (Figure 5). Within Caucasian populations, supernumerary teeth most commonly affect the permanent dentition, being seen in up to 3.2% of the population, generally occurring as a localized anomaly affecting one or two teeth and predominating in the anterior maxilla 76,77.…”

Section: Anomalies Of Tooth Numbermentioning

confidence: 99%

Diseases of the tooth: the genetic and molecular basis of inherited anomalies affecting the dentition

Cobourne

Sharpe

2012

WIREs Developmental Biology

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In humans, inherited variation in the number, size, and shape of teeth within the dentitions are relatively common, while rarer defects of hard tissue formation, including amelogenesis and dentinogenesis imperfecta, and problems associated with tooth eruption are also seen. In many cases, these anomalies occur in isolation, but they can also present as a feature of numerous well-characterized developmental syndromes. Complex reiterative signaling between the epithelium and mesenchyme is a feature of normal tooth development in the embryo, occurring from early patterning through morphogenesis, hard tissue formation and during root development. Significant events also occur during postnatal development of the dentition, including hard tissue maturation and tooth eruption. In the last decade, advances in human and mouse genetics have meant that in many cases candidate genes have been identified for these anomalies. These genes have provided a useful platform for developmental biologists, allowing them to begin elucidating how these signals interact to generate a functional dentition and understand the mechanisms underlying many of the anomalies that are seen in human populations. In this article, we review current concepts relating to the developmental biology of tooth number, size, and shape, formation of the dental hard tissues and eruption of the tooth into the oral cavity. We will focus on the molecular mechanisms underlying these processes in both health and disease.

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Section: Anomalies Of Tooth Numbermentioning

confidence: 99%

Diseases of the tooth: the genetic and molecular basis of inherited anomalies affecting the dentition

Cobourne

Sharpe

2012

WIREs Developmental Biology

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“…These often lie palatal to the incisor ( Figure 1) and develop as a fragmentation from the dental lamina 9 due to loss of function of the Sprouty genes (Spry2 & Srpy4) 10 …”

Section: Supernumerary Teethmentioning

confidence: 99%

The aberrant central incisor

et al. 2017

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“…The supernumerary teeth (SNT) or hyperodontia is a developmental alteration expressed as teeth formed in excess of the normal dental formula (Ashkenazi et al, 2007) that may occur singly or multiple, uni or bilaterally and in one or both jaws (Kara et al, 2012), with shape and size usually consistent with the dentition in the region of the jaw in which they are localized or with little or no resemblance (Fleming et al, 2010) and it may be encountered as a chance finding during routine radiographic evaluation or as the cause of an impacted teeth (Garvey et al, 1999).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Supernumerary Teeth on Panoramic Radiographs in a Non-Adult Peruvian Sample

Pérez¹,

Chávez

Ponce³

2014

Int. J. Odontostomat.

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ABSTRACT:The design of the present study was transversal and descriptive, the objective was to determine the prevalence and distribution of supernumerary teeth in panoramic radiography from Peruvians in Lima -Peru. The panoramic radiography of 1754 non-syndromic patients between 3 to 20 years of age were evaluated in order to determine the presence of supernumerary teeth and associated variables like number of supernumerary teeth, affected jaw and region, type according to shape, type according to location, eruption status and complications. The prevalence of supernumerary teeth was 4.62% (81 patients, 113 supernumerary teeth), 2.22% in females (39 patients, 53 supernumerary teeth) and 2.4% and in the males (42 patients, 60 supernumerary teeth). A singly supernumerary tooth (72.8%), in the maxilla (72.8%) and the antero-superior region (55.8%) was the most frequent presentation; the conical (39%) and supplementary shape (25.6%) along with the anterior supernumerary teeth (34.5%) and parapremolar supernumerary teeth (31.9%) were the most frequent shape an location found; the intraosseous (46.9%) and impacted (24.8%) were the most frequent eruption status found; and the malposition of nearby teeth (38.1%) was the most frequent complication. The prevalence of supernumerary teeth in Peruvians was higher than that reported in the literature and the distribution of the supernumerary teeth associated variables was similar to those reported in the literature.

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Revisiting the supernumerary: the epidemiological and molecular basis of extra teeth

Cited by 72 publications

References 50 publications

Diseases of the tooth: the genetic and molecular basis of inherited anomalies affecting the dentition

Diseases of the tooth: the genetic and molecular basis of inherited anomalies affecting the dentition

The aberrant central incisor

Prevalence of Supernumerary Teeth on Panoramic Radiographs in a Non-Adult Peruvian Sample

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