Revisited Localization of Cajal Cells in Smooth Muscles of Different Organs

Abstract

Smooth muscle tissue represents a complicated and dynamical ensemble of smooth muscle cells characterized by different structural-methabolical parameters. In the composition of smooth muscle tissue a group of cell elements (cells of Cajal, ICC) is incorporated. Their structural organization and localization in smooth muscle tissue allow to consider them an important component of the system responsible for functional activity regulation. The goal of the study was to get a reliable technology for ICC isolation. The method of the alkaline cell dissociation was used. Isolated smooth cells of different organs were studied. Our findings have shown that the cells we have got by the method of cell dissosiation had clear stable morphological parameters of the interstitial cells of Cajal.