Numerous studies have attempted to solve the problems constraining the sustainable utilization of nuclear power, for example, the already accumulated HLWs, the worsening environment due to greenhouse emissions, the questionable reliability of natural uranium resources, and the argument over nuclear safety, which are certainly top issues to be addressed. A well-organized nuclear fuel cycle system is the basis for nuclear power sustainability. Therefore, which type of reactor to be employed and whether or not to adopt a reprocessing technique for spent fuel are two key issues to be addressed. A Sodium Fast Reactor (SFR), a Generation IV reactor, has gained considerable attention worldwide. SFR recycling coupled to pyroprocessing, a so-called Pyro-SFR Recycling, shows promising advantages, and therefore, this paper focuses on exploring a strategy of how to realize it, which can offer informative procedures for a better use of nuclear power. A dynamic model has been developed to quantitatively analyze a countryspecific case employing two scenarios, a once-through and Pyro-SFR, for a comprehensive comparison, especially focusing on the uranium utilization, the HLW reduction, and the electricity generation cost.