Review of Allogeneic Dentin Graft for Maxillofacial Bone Defects

Ku, Jeong-Kui; Jeong, Yeong Kon; Um, In-Woong

doi:10.1089/ten.tec.2021.0152

Cited by 6 publications

(2 citation statements)

References 63 publications

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“…Various studies have proven the osteoinductive capability of demineralized dentin matrix, which can recruit mesenchymal cells and differentiate them into osteoblasts. [17][18][19] Especially, recent studies have reported the safety and e cacy of allogeneic DDM [19][20][21], we transplanted Allo-DDM (HuBT, Korea Tooth Bank, Republic of Korea) in patients who consented to the study. All cases showed no rejection or infection post-transplantation and achieved excellent soft tissue healing.…”

Section: Discussionmentioning

confidence: 99%

RETRACTED: Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants

Park,

Jee,

Yoon

et al. 2024

Preprint

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Background The decision of surgical margin for Medication-Related Osteonecrosis of the Jaw (MRONJ) surgery is challenging. Recently, a method involving biofluorescence imaging system (BIS) has been reported for its application in MRONJ surgery to live detection of pathologic bone tissue from vital bone, which cannot be distinguished during conventional surgery. This case series aimed to assess the outcomes of adjacent teeth and implants near the lesion site in MRONJ patients who underwent BIS-guided MRONJ surgery. Methods We retrospectively assessed the radiographic and clinical outcomes of seven patients who underwent MRONJ surgery with BIS guidance but chose not to remove adjacent teeth or implants near the lesion. Result A total of five female patients (77.2 ± 4.7 years) were included in the study. Three implants and two teeth adjacent to the lesion were preserved. Over an average duration of 8.7 months, all subjects exhibited normal soft tissue healing and function without any complications. Conclusion The BIS guided MRONJ surgery can be considered a minimally invasive and effective approach.

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Section: Discussionmentioning

confidence: 99%

RETRACTED: Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants

Park,

Jee,

Yoon

et al. 2024

Preprint

Self Cite

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“…The chemical components of dentin are almost identical to those of bone: They both consist of collagen (18%), non-collagenous proteins (2%), hydroxyapatite (HAp) (70%), and body fluid (10%; all in weight / volume ) [ 13 , 21 ]. DDM scaffolds naturally possess collagen ligands in the form of Arg-Gly-Asp (RGD)-binding sequences, which explains their excellent tissue compatibility, cell attachment capability (which resembles that of osteoblasts), and absorbability for remodeling at the cellular level [ 12 , 13 , 22 ]. Bessho et al extracted BMPs from bone and dentin matrix, and concluded that they exhibit the same osteoinductivity in the body [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Impact of Autogenous Demineralized Dentin Matrix on Mandibular Second Molar after Third Molar Extraction: Retrospective Study

Kim

et al. 2022

JFB

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The purpose of this retrospective study was to evaluate bone healing after autogenous demineralized dentin matrix (DDM) grafts, focusing on the distal root of the mandibular second molar after the extraction of the third. We included retrospective data from 20 patients who had undergone molar extractions (15 male, 41.9 ± 12.0 years) between January 2020 and September 2022 and had DDM grafts implanted on the extraction socket, immediately (“immediate graft”) or 6 weeks (“delayed graft”) after the first surgery without primary closure. Patients who underwent grafting on only one side were used as the control group (n = 4). Bone defects at the mandibular second molar were measured preoperatively and 4 months after the graft surgery using cone-beam computed tomography (CBCT). Improvement of bone defect (i.e., the change in the bony defect pre- vs. postoperatively) was compared between the control and graft groups using the Wilcoxon Signed Rank test, and the difference between immediate and delayed grafts was analyzed with the Mann-Whitney U test. Complications such as infections or graft failure did not occur. Although pre-operative defects were smaller in the control than in the graft group (2.98 ± 1.77 and 10.02 ± 3.22 mm, p = 0.001), post-operative defects were similar in both (2.12 ± 0.59 and 2.29 ± 1.67 mm, respectively). The improvement ratio was not statistically significant in the control group (22.68 ± 15.36%) but a difference was observed in the graft group (76.70 ± 15.36%, p = 0.001). The amount of improvement of bone defect was not affected by graft timing or patient sex. In conclusion, DDM can improve bone defect at the distal aspect of the mandibular second molar after third molar extraction.

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Hyaluronic acid-mediated collagen intrafibrillar mineralization and enhancement of dentin remineralization

Shao

Shi

et al. 2023

Carbohydrate Polymers

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Review of Allogeneic Dentin Graft for Maxillofacial Bone Defects

Cited by 6 publications

References 63 publications

RETRACTED: Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants

RETRACTED: Biofluorescence imaging system (BIS) Guided surgery for MRONJ: A Case Series on the Preservation of Teeth and Implants

Impact of Autogenous Demineralized Dentin Matrix on Mandibular Second Molar after Third Molar Extraction: Retrospective Study

Hyaluronic acid-mediated collagen intrafibrillar mineralization and enhancement of dentin remineralization

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