Review: Bahan Alami Penyembuh Luka

Oktaviani, Dede Jihan; Widiyastuti, Shella; Maharani, Dian Amalia; Amalia, Agni Nur; Ishak, Asep Maulana; Zuhrotun, Ade

doi:10.24198/farmasetika.v4i3.22939

Cited by 20 publications

(20 citation statements)

References 1 publication

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“…Luka lecet biasanya disebabkan oleh gesekan dengan benda keras. Luka robek biasanya disebabkan oleh benda keras yang merusak permukaan kulit, 22 sedangkan luka memar merupakan perdarahan akibat pembuluh darah kapiler dan vena dalam jaringan bawah kulit yang pecah. 23 Bila ditinjau berdasarkan jenis luka maka tiap luka pada penelitian ini berjumlah sama, yaitu masing-masing jenis terdapat tiga luka (33,3%).…”

Section: Bahasanunclassified

Forensic Findings in Exhumation Cases in North Sulawesi in 2019-2020

Kasenda

Kristanto

Mallo

2022

eCL

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Exhumation is a procedure of removing a corpse carried out for medicolegal investi-gations, relocation, or other purposes. This study aimed to determine the overview of forensic findings in exhumation cases in North Sulawesi during the years 2019-2021. This was a descriptive and retrospective study using data of Visum et Repertum. The results obtained five cases of exhumation during the period of January 2019-August 2021. In year 2019 there was the most frequent exhumation performed, namely three cases (60%). Based on sex, three (60%) corpses were female. In 80% of the cases, the cause of death could still be determined, while in 20% of cases could not be determined anymore. Age was dominated by the adult age group, namely 26-45 year olds. The pattern of the wounds found were blisters, bruises, and lacerations with the same number and the most common location was in the head area. In conclusion, most of the forensic findings in exhumation cases in North Sulawesi registered at Prof. Dr. R. D. Kandou Hospital Manado year 2019-2021 could reveal the most common cause of death, namely blunt force trauma with bruises, abrasions, as well as lacerations, and head as the most common site of injury.Keywords: exhumation; forensic findings Abstrak: Ekshumasi merupakan prosedur penggalian jenazah yang dilakukan untuk kepentingan investigasi medikolegal, relokasi, ataupun tujuan lainnya. Penelitian ini bertujuan untuk mengetahui gambaran temuan forensik pada kasus ekshumasi di Sulawesi Utara tahun 2019-2021. Jenis penelitian ialah deskriptif retrospektif dengan menggunakan Visum et Repertum. Hasil penelitian mendapatkan lima kasus ekshumasi selama periode Januari 2019-Agustus 2021. Tahun 2019 merupakan tahun dengan kasus ekshumasi terbanyak yaitu sebanyak tiga kasus (60%). Jenis kelamin paling banyak ialah jenazah perempuan dengan jumlah tiga kasus (60%). Pada 80% kasus ekshumasi dapat ditentukan sebab kematiannya, sedangkan pada 20% tidak dapat ditentukan lagi. Usia didominasi oleh kelompok usia dewasa yaitu 26-45 tahun. Pola luka yang ditemukan ialah luka lecet, luka memar, dan luka robek dengan jumlah yang sama serta lokasi terbanyak ditemukan ialah pada daerah kepala. Simpulan penelitian ini ialah sebagian besar temuan forensik pada kasus ekshumasi di Sulawesi Utara yang tercatat di RSUP Prof. Dr. R. D. Kandou tahun 2019-2021 dapat mengungkapkan sebab kematian, yang terbanyak yaitu kekerasan tumpul dengan jumlah luka memar, lecet, dan robek yang sama serta lokasi cedera tersering pada kepala.Kata kunci: ekshumasi; temuan forensik

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Section: Bahasanunclassified

Forensic Findings in Exhumation Cases in North Sulawesi in 2019-2020

Kasenda

Kristanto

Mallo

2022

eCL

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“…Luka dapat terjadi secara sengaja maupun tidak sengaja. Luka secara sengaja, seperti luka karena pembedahan, sedangkan secara tidak sengaja contohnya luka terkena benda tajam maupun tumpul, luka karena kecelakaan dan pasca pembedahan (Oktaviani et al, 2019).…”

Section: Pendahuluanunclassified

“…Pengobatan terhadap infeksi luka yang disebabkan oleh bakteri S. aureus yaitu antibiotik, antara lain golongan penisilin, makrolida, aminoglikosida dan golongan sefalosporin. Pada perawatan luka dilakukan dengan membersihkan luka untuk mengurangi kontaminasi pada luka menggunakan air dan cairan antiseptic seperti povidone-iodine, hydrogen peroksida (Oktaviani et al, 2019). Penggunaan obat untuk luka seperti antibiotik memiliki efek samping dan memerlukan dana cukup mahal.…”

Section: Pendahuluanunclassified

Anti-Bacterial Activity Test of Ethanol Extracts and Ethlacetate Fraction From the Extract of Jatropha Curcas L. Leaves Against Staphylococcus Aureus

Wulandari¹

2021

J Vocat Heal Stud

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Background: Staphylococcus aureus is a gram-positive bacteria that can cause infection. One of the plants that has antibacterial activity is jatropha leaves which contain flavonoids, saponins, tannins, alkaloids, steroids and polyphenols. Purpose: To determine the antibacterial activity of ethanol extract and ethyl acetate fraction with concentrations of 30%, 60% and 100% against Staphylococcus aureus bacteria. Method: The method for extracting jatropha leaves is maceration with 96% ethanol solvent and the fractionation method, namely liquid-liquid fractionation with ethyl acetate solvent. Antibacterial activity test was carried out in vitro with the disc diffusion method and compared the mean zone of inhibition of each treatment with a positive control (gentamicin 10 μg). Result: The results showed that the ethanol extract and ethyl acetate fraction of jatropha leaves had a strong resistance response, while the positive control gave a very strong inhibitory response to the growth of S. aureus bacteria. Based on the one way ANOVA test, ethanol extract and ethyl acetate fraction showed a significant difference from each treatment with a significant value (P=<0.05). Conclusion: The ethanol extract of Jatropha leaves can inhibit the growth of S. aureus bacteria at a concentration of 100% (18.28 ± 0.50 mm), 100% concentration of ethyl acetate fraction (15.10 ± 0.12 mm). The ethanol extract provided the best inhibition power, namely 18.28 ± 0.50 mm and a positive control 21.82 ± 0.092 mm.

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“…Wound healing is a complex change process in restoring anatomical continuity and function (Oktaviani et al, 2019). One of the wound treatments can be done by using herbal ingredients, namely papaya leaves (Carica papaya) (Dewi & Wicaksono, 2020).…”

Section: Introductionmentioning

confidence: 99%

Effect of Papaya Leaf Extract Gel (Carica papaya) on Incision Wound Healing in Rattus norvegicus

Marlinawati

Nurhidayah²,

Santoso³

et al. 2022

Med.Lab.Tech.J.

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Carica papaya is one kind of herbal plant that can help the wound healing process. Scientifically, the leaves of papaya are proven to have anti-inflammatory effects. Flavonoid, alkaloid, tannin, and saponin compounds in papaya leaves have antimicrobial and antioxidant properties to accelerate the re-epithelization and cell migration needed for wound healing. This research aims to determine the effect of papaya leaf extract gel (Carica papaya) on the healing of incision wounds in Rattus norvegicus based on changes in wound morphology (signs of redness, edema, pus, granulation, moisture, and wound length). This research used female Rattus norvegicus aged 12-16 weeks weighing 180-200 grams, divided into five groups (NaCl 0,9%, povidone-iodine, papaya leaf extract gel with concentrations of 10%, 20%, and 30%). Incision wounds on the back of the rat with a length of 2 cm and depth of 1 cm. The normality test used the Shapiro-Wilk test, and the homogeneity test used the Levene test. The research data were not normally distributed nor homogeneous, so they were analyzed using the Kruskal Wallis and Mann-Whitney tests. The results showed that the extract of papaya leaves with concentrations of 10%, 20%, and 30% had significant differences in positive and negative control groups in the wound healing process with the differences in redness (p=0.038), granulation tissue (p=0.039), moistures (0,48), and wound length (p=0,049). It can be concluded that papaya leaf extract gel (Carica papaya) is effective in accelerating the healing process of incision wounds in Rattus norwegicus at concentrations of 10%, 20%, and 30%, so for further research, it is hoped that a histopathological examination can be carried out so that changes that occur in collagen, neutrophile cells, monocytes, and lymphocytes are seen.

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Review: Bahan Alami Penyembuh Luka

Cited by 20 publications

References 1 publication

Forensic Findings in Exhumation Cases in North Sulawesi in 2019-2020

Forensic Findings in Exhumation Cases in North Sulawesi in 2019-2020

Anti-Bacterial Activity Test of Ethanol Extracts and Ethlacetate Fraction From the Extract of Jatropha Curcas L. Leaves Against Staphylococcus Aureus

Effect of Papaya Leaf Extract Gel (Carica papaya) on Incision Wound Healing in Rattus norvegicus

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