Revascularization and healing of onlay particulate allogeneic bone grafts in primates

Healing of onlay mandibular bone grafts covered with collagen membrane or bovine bone substitutes: A microscopical and immunohistochemical study in the sheep

“…This is in agreement with earlier reports 3,11,[13][14][15]18,23 . VERHOEVEN et al 51 reported that in the first year after bone grafting, resorption is significant and may continue for years.…”

“…Cortical bone graft for example, may lose up to 33% of its strength during incorporation and generally remodels over a 6-18-month period. 17 FONSECA et al 18 also reported that laying corticocancellous bone onto the mandibular buccal cortex for augmentation of the alveolar ridge is a poor method by which to change ridge morphological structure. Several factors like embryological origin, architecture, orientation, and graft dimension have been suggested as reasons for the poor volume maintenance of the autogenous bone grafts.…”

Healing of onlay mandibular bone grafts covered with collagen membrane or bovine bone substitutes: A microscopical and immunohistochemical study in the sheep

“…This is in agreement with earlier reports 3,11,[13][14][15]18,23 . VERHOEVEN et al 51 reported that in the first year after bone grafting, resorption is significant and may continue for years.…”

“…Cortical bone graft for example, may lose up to 33% of its strength during incorporation and generally remodels over a 6-18-month period. 17 FONSECA et al 18 also reported that laying corticocancellous bone onto the mandibular buccal cortex for augmentation of the alveolar ridge is a poor method by which to change ridge morphological structure. Several factors like embryological origin, architecture, orientation, and graft dimension have been suggested as reasons for the poor volume maintenance of the autogenous bone grafts.…”

Biomechanical evaluation of rat skull defects, 1, 3, and 6 months after implantation with osteopromotive substances

“…In the present study, the biomechanical strength of defects filled with BC was higher than the strength of defects filled with HA and unfilled controls, but significantly lower than the strength of defects filled with DBM. The biomechanical data obtained in the present study supports those by Fonseca et al (1980Fonseca et al ( , 1983 suggesting that incorporation of autogenous bone grafts is associated with an intense osteoclastic activity in the initial stages to remove the transplanted bone along with rapid fibrous tissue ingrowth. The net result of this intense osteogenic induction is accompanied by increased resorption of bone and subsequent lower strength than grafting with DBM (Fonseca et al, 1980(Fonseca et al, , 1983.…”

Human Bone Repair After Mandibular Symphysis Block Harvesting: A Clinical and Tomographic Study

“…Phase 2, or osteoinduction by osteoclastic secretion of promoter proteins, entails the release of bone morphogenetic proteins and osteogenin that will activate the transformation of pluripotent mesenchymal cells into osteoblasts. 7,24,25 A typical finding in the present study was the formation of a well-defined buccal cortical plate in group B ( ‡24 months of healing time) patients covering the medullar osseous trabecular pattern (Fig. 4B).…”

Healing of onlay mandibular bone grafts covered with collagen membrane or bovine bone substitutes: A microscopical and immunohistochemical study in the sheep

“…This is in agreement with earlier reports 3,11,[13][14][15]18,23 . VERHOEVEN et al 51 reported that in the first year after bone grafting, resorption is significant and may continue for years.…”

“…Cortical bone graft for example, may lose up to 33% of its strength during incorporation and generally remodels over a 6-18-month period. 17 FONSECA et al 18 also reported that laying corticocancellous bone onto the mandibular buccal cortex for augmentation of the alveolar ridge is a poor method by which to change ridge morphological structure. Several factors like embryological origin, architecture, orientation, and graft dimension have been suggested as reasons for the poor volume maintenance of the autogenous bone grafts.…”

Biomechanical evaluation of rat skull defects, 1, 3, and 6 months after implantation with osteopromotive substances

“…In the present study, the biomechanical strength of defects filled with BC was higher than the strength of defects filled with HA and unfilled controls, but significantly lower than the strength of defects filled with DBM. The biomechanical data obtained in the present study supports those by Fonseca et al (1980Fonseca et al ( , 1983 suggesting that incorporation of autogenous bone grafts is associated with an intense osteoclastic activity in the initial stages to remove the transplanted bone along with rapid fibrous tissue ingrowth. The net result of this intense osteogenic induction is accompanied by increased resorption of bone and subsequent lower strength than grafting with DBM (Fonseca et al, 1980(Fonseca et al, , 1983.…”

Human Bone Repair After Mandibular Symphysis Block Harvesting: A Clinical and Tomographic Study

“…Phase 2, or osteoinduction by osteoclastic secretion of promoter proteins, entails the release of bone morphogenetic proteins and osteogenin that will activate the transformation of pluripotent mesenchymal cells into osteoblasts. 7,24,25 A typical finding in the present study was the formation of a well-defined buccal cortical plate in group B ( ‡24 months of healing time) patients covering the medullar osseous trabecular pattern (Fig. 4B).…”

Healing of onlay mandibular bone grafts covered with collagen membrane or bovine bone substitutes: A microscopical and immunohistochemical study in the sheep

“…This is in agreement with earlier reports 3,11,[13][14][15]18,23 . VERHOEVEN et al 51 reported that in the first year after bone grafting, resorption is significant and may continue for years.…”

“…Cortical bone graft for example, may lose up to 33% of its strength during incorporation and generally remodels over a 6-18-month period. 17 FONSECA et al 18 also reported that laying corticocancellous bone onto the mandibular buccal cortex for augmentation of the alveolar ridge is a poor method by which to change ridge morphological structure. Several factors like embryological origin, architecture, orientation, and graft dimension have been suggested as reasons for the poor volume maintenance of the autogenous bone grafts.…”

Biomechanical evaluation of rat skull defects, 1, 3, and 6 months after implantation with osteopromotive substances

“…In the present study, the biomechanical strength of defects filled with BC was higher than the strength of defects filled with HA and unfilled controls, but significantly lower than the strength of defects filled with DBM. The biomechanical data obtained in the present study supports those by Fonseca et al (1980Fonseca et al ( , 1983 suggesting that incorporation of autogenous bone grafts is associated with an intense osteoclastic activity in the initial stages to remove the transplanted bone along with rapid fibrous tissue ingrowth. The net result of this intense osteogenic induction is accompanied by increased resorption of bone and subsequent lower strength than grafting with DBM (Fonseca et al, 1980(Fonseca et al, , 1983.…”

Human Bone Repair After Mandibular Symphysis Block Harvesting: A Clinical and Tomographic Study

“…Phase 2, or osteoinduction by osteoclastic secretion of promoter proteins, entails the release of bone morphogenetic proteins and osteogenin that will activate the transformation of pluripotent mesenchymal cells into osteoblasts. 7,24,25 A typical finding in the present study was the formation of a well-defined buccal cortical plate in group B ( ‡24 months of healing time) patients covering the medullar osseous trabecular pattern (Fig. 4B).…”